CCAPD: Alignment of Alcohol Dehydrogenase 1 (ADH1), Alpha Isozyme for primates

10 20 30 40 50 60 ----:----|----:----|----:----|----:----|----:----|----:----| Consensus sTAGKVIKCKAAVlWExkKPfsIEEVEVAPPQAhEVRIKMVAtGICrSDdhvVsgxLxxx ==================================================================================================== * GADUS_MORHUA aTvGKVIKCKAAVaWEanKPlvIEEIEVdvPhANEIRIKIIATGVChTDlyhLfegkhkd * Danio_rerio aTAGKVIKCRAAVaWEpKaPlmMEEIEVAPPQegEIRIKVIATGLChTDlyhLvdg-dkr * Oryzias_latipes aTAGKVIKCKAAVaWEpnKPlvIEDIEVAPPQANEVRIKIVATGVChTDlyhLfegMhkd ==================================================================================================== * HUMAN STAGKVIKCKAAVLWElKKPFSIEEVEVAPPKAHEVRIKMVAvGICgTDDHVVSGtMv-t * HORSE STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtLv-t * 1A71A_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtLv-t * 1AXEA_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtLv-t * 1AXGA_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtLv-t * 1JU9A_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtLv-t * 1MGOA_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtLv-t * 1N8KA_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtLv-t * 1QLHA_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtLv-t * 1QV6A_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDqVVSGtLv-t * Apteryx_australis STAGKVIKCKAAVLWEpKKPFSIEEVEVAPPKAHEVRIKILATGICRSDDHVITGaLv-r * Canis_lupus STAGKVIKCKAAVLWElKKPFSIEEVEVAPPKAHEVRIKMVASGICRSDDHVVTGaLv-v * Coturnix_coturnix STAGKVIKCKAAVLWEanKPFSLEEVEVAPPKAHEVRIKIVATGICRSDDHVVTGaLa-m * Chicken STvGKVIKCKAAVLWEanKPFSLEEVEVAPPKAHEVRIKIVATGICRSDDHVVTGaLa-m * Macaca_mulatta STAGKVIKCKAAVLWEvmKPFSIEDVEVAPPKAyEVRIKMVtvGICgTDDHVVSGtMv-t * Mouse STAGKVIKCKAAVLWElhKPFTIEDIEVAPPKAHEVRIKMVATGVCRSDDHVVSGtLv-t * Rabbit STAGKVIKCKAAVLWQlnKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHaVTGsIa-v * Pan_troglodytes STAGKVIKCKAAVLWElKKPFSIEEVEVAPPKAHEVRIKMVAvGICgTDDHVVSGtMv-t * Pongo_pygmaeus STAGKVIKCKAAVLWElKKPFSIEEVEVAPPKAqEVRIKMVAvGICgTDDHVVSGtMv-t * X_laevis aTAGKVIKCKAAIaWgpKQPlTIEDIEVAPPKAHEVRVKIVATGICRSDDHVLSGaIsdm * X_tropicalis aTAGKVIKCKAAVaWgpKQPlTIEDIEVAPPKAHEVRVKIVATGICRSDDHVLSGaIsdm * Rat-ADH1 STAGKVIKCKAAVLWEphKPFTIEDIEVAPPKAHEVRIKMVATGVCRSDDHaVSGsLf-t * Rat-Q8K571 STAGKVIKCKAAVLWEphKPFTIEDIEVAPPKAHEVRIKMVATGVCRSDDHaVSGsLf-t * Struthio_camelus-ADH1 STAGKVIKCKAAVLWEpKKPFSIEEVEVAPPKAHEVRVKIIATGICRSDDHVISGvLv-m * Struthio_camelus-ADH1_VAR STAGKVIKCKAAVLWEpKKPFSIEEVEVAPPKAHEVRVKIIATGICRSDDHVISGvLv-m * Alligator_mississippiensis-ADH1 STAGKVIKCKAAItWEiKKPFSIEEIEVAPPKAHEVRIKILATGICRSDDHVtaGlLt-m * Alligator_mississippiensis-ADH1_VAR_1 STAGKVIKCKAAItWEiKKPFSIEEIEVAPPKAHEVRIKILATGICRSDDHVtaGlLt-m * Alligator_mississippiensis-ADH1_VAR_2 STAGKVIKCKAAItWEiKKPFSIEEIEVAPPKAHEVRIKILATGICRSDDHVtaGlLt-m ==================================================================================================== Consensus sTAGKVIKCKAAVlWExkKPfsIEEVEVAPPQAhEVRIKMVAtGICrSDdhvVsgxLxxx 70 80 90 100 110 120 ----:----|----:----|----:----|----:----|----:----|----:----| Consensus pxPvILGHEaAGIVESIGeGVSslKPGDKVIPLwvpQCGKCkxCknpKsNxClKxndLxs ==================================================================================================== * GADUS_MORHUA gfPVVLGHEgAGIVESVGpGVTefQPGEKVIPLFIsQCGECRfCQSPKTNqCVK-gwa-N * Danio_rerio gfPVVLGHEsAGVVESVGpGVTdyKPGDKVIPLFLsQCGKCKfCKcPKTNlCes-Swa-T * Oryzias_latipes gfPaVLGHEgAGIVESVGpGVSefQPGDRVIPLFIsQCrECRfCKSPKTNqCeK-gwa-a ==================================================================================================== * HUMAN PlPVILGHEAAGIVESVGEGVTTVKPGDKVIPLaIPQCGKCRiCKNPESNyCLK-NDV-S * HORSE PlPVIaGHEAAGIVESIGEGVTTVRPGDKVIPLFtPQCGKCRvCKHPEgNfCLK-NDL-S * 1A71A_Horse PlPVIaGHEAAGIVESIGEGVTTVRPGDKVIPLWtPQCGKCRvCKHPEgNfCLK-NDL-S * 1AXEA_Horse PlPVIaGHEAAGIVESIGEGVTTVRPGDKVIPLWtPQCGKCRvCKHPEgNfCLK-NDL-S * 1AXGA_Horse PlPVIaGHEAAGIVESIGEGVTTVRPGDKVIPLFtPQCGKCRvCKHPEgNfCLK-NDL-S * 1JU9A_Horse PlPVIaGHEAAGIVESIGEGVTTVRPGDKVIPLFtPQCGKCRvCKHPEgNfCLK-NDL-S * 1MGOA_Horse PlPVIaGHEAAGIVESIGEGVTTVRPGDKVIPLatPQCGKCRvCKHPEgNfCLK-NDL-S * 1N8KA_Horse PlPVIaGHEAAGIVESIGEGVTTVRPGDKVIPLFtPQCGKCRvCKHPEgNfCLK-NDL-S * 1QLHA_Horse PlPVIaGHEAAGIVESIGEGVTTVRPGDKVIPLFtPQCGKCRvCKHPEgNfCLK-NDL-S * 1QV6A_Horse PlPVIaGHEAAGIVESIGEGVTTVRPGDKVIPLFtPQCGKCRvCKHPEgNfCLK-NDL-S * Apteryx_australis PfPIILGHEAAGVVESVGEGVTSVKPGDKVIPLFVPQCGECsaClStKgNlCsK-NDI-g * Canis_lupus PlPIILGHEAAGIVESIGEGVTTVKPGDKVIPLFtPQCGKCnvCKHPQgNlCVK-NDL-S * Coturnix_coturnix PfPVILGHEAAGVVESVGEkVTlLKPGDaVIPLFVPQCGECRsClStKgNlCIK-NDLsS * Chicken PfPIILGHEAAGVIESVGEkVTSLKPGDaVIPLFVPQCGECRsClStKgNlCIK-NDLsS * Macaca_mulatta PlPVILGHEAAGIVESVGEGVTTVEPGDKVIPLaLPQCGKCRiCKtPErNyCLK-NDV-S * Mouse PlPaVLGHEgAGIVESVGEGVTcVKPGDKVIPLFsPQCGECRiCKHPESNfCsR-SDL-l * Rabbit PlPVILGHEAAGIVESIGEGVTTVKPGDKVIPLFtPQCGKCRiCKHPESNfCLi-NDL-g * Pan_troglodytes PlPVILGHEAAGIVESVGEGVTTVKPGDKVIPLaLPQCGKCRiCKNPESNyCLK-NNV-N * Pongo_pygmaeus PlPaILGHEAAGIVESVGEGVTTVKPGDKVIPLaVPQCGKCRiCKNPESNyCLK-NDV-S * X_laevis kfPaILGHEgAGIVESVGEGVkNIKPGDKVIPLFVPQCGECRsCtNsRSNlCdK-HDI-g * X_tropicalis kfPaILGHEgAGIVESVGEGVkNIKPGDKVIPLFVPQCGECRcCtNvRSNlCdK-HDI-g * Rat-ADH1 PlPaVLGHEgAGIVESIGEGVTcVKPGDKVIPLFsPQCGKCRiCKHPESNlCcQtkNL-T * Rat-Q8K571 PlPaVLGHEgAGIVESIGEGVTcVKPGDKVIPLFsPQCGKCRiCKHPESNlCcQtkNL-T * Struthio_camelus-ADH1 PfPIILGHEAAGVVESVGEGVTSVKPGDKVIPLFVPQCGECsvClStKgNlCrK-NDI-g * Struthio_camelus-ADH1_VAR PfPIILGHEAAGVVESVGEGVTSVKPGDKVIPLFVPQCGECsvClStKgNlCcK-NDI-g * Alligator_mississippiensis-ADH1 PlPMILGHEAAGVVEStGEGVTSLKPGDKVIPLFVPQCGECmpClksngNlCIR-NDL-g * Alligator_mississippiensis-ADH1_VAR_1 PlPMILGHEAAGVVEStGEGVTSLKPGDKVIPLFVPQCGECmpClksngNlCIR-NDL-g * Alligator_mississippiensis-ADH1_VAR_2 PlPMILGHEAAGVVEStGEGVTSLKPGDKVIPLFVPQCGECmpClksngNlCIR-NDL-g ==================================================================================================== Consensus pxPvILGHEaAGIVESIGeGVSslKPGDKVIPLwvpQCGKCkxCknpKsNxClKxndLxs 130 140 150 160 170 180 ----:----|----:----|----:----|----:----|----:----|----:----| Consensus xxpxxxgxmxdgTSRFTCRGKxIhnFLgtSTFSQYTVVNExaVAKIDaaaPLEKVCLIGC ==================================================================================================== * GADUS_MORHUA esPdvmsp---keTRFTCKGRkVlqFLGTSTFSQYTVVNQiAVAKIDpsAPLDtVCLLGC * Danio_rerio kyhdimae---pTSRFTCRGQtIlqFMGTSTFSEYTVINQnAVAKIDenAPLDRVfLLGC * Oryzias_latipes dhydvmal---adSRFTCKGKkVlqFMGaSTFSEYTVMNQiAVAKIDpAAPLDKVCLLGC ==================================================================================================== * HUMAN -nP-q-GtLqDGTSRFTCRrKpIHHFLGiSTFSQYTVVDEnAVAKIDAAsPLEKVCLIGC * HORSE -mP-r-GtMqDGTSRFTCRGKpIHHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGC * 1A71A_Horse -mP-r-GtMqDGTSRFTCRGKpIHHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGC * 1AXEA_Horse -mP-r-GtMqDGTSRFTCRGKpIHHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGC * 1AXGA_Horse -mP-r-GtMqDGTSRFTCRGKpIHHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGC * 1JU9A_Horse -mP-r-GtMqDGTSRFTCRGKpIHHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGC * 1MGOA_Horse -mP-r-GtMqDGTSRFTCRGKpIHHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGC * 1N8KA_Horse -mP-r-GtMqDGTSRFTCRGKpIHHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGC * 1QLHA_Horse -mP-r-GtMqDGTSRFTCRGKpIHHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGC * 1QV6A_Horse -mP-r-GtMqDGTSRFTCRGKpIHHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGC * Apteryx_australis -sa-s-GlMpDGTTRFTCKGKaIHHFIGTSTFTEYTVVHEtAVAKIaAAAPLEKVCLIGC * Canis_lupus -kP-r-GtLqDGTiRFTCRGKpIyHFLGiSTFSQYTVVDEfsVAKIDAAsPLEKVCLIGC * Coturnix_coturnix -sP-t-GlMaDGTTRFTCKGKaIHHFIGTSTFTEYTVVHEtAaAKIDsAAPLEKVCLIGC * Chicken -sP-t-GlMaDGTTRFTCKGKaIHHFVGTSTFTEYTVVHEtAaAKIDsAAPLEKVCLIGC * Macaca_mulatta -nP-r-GtLqDGTSRFTCRGKpIHHFLGvSTFSQYTVVDEnAVAKIDAAsPMEKVCLIGC * Mouse -mP-r-GtLrEGTSRFSCKGKqIHNFIsTSTFSQYTVVDDiAVAKIDgAsPLDKVCLIGC * Rabbit -kP-k-GmLlDGTSRFTCKGKpIHHFIGTSTFSQYTVVDEiAVAKIDAAAPLEKVCLIGC * Pan_troglodytes -nP-q-GtLqDGTSRFTCRGKpIHHFLGiSTFSQYTVVDEnAVAKIDAAsPLEKVCLIGC * Pongo_pygmaeus -nP-q-GtLqDGTSRFTCRGKpIHHFLGiSTFSQYTVVDEnAVAKIDAAsPLaKVCLIGC * X_laevis -py-i-GlLlDkTSRiTCKGKpVyNFLsTSTFTEYTVLDEicVAKIDdnAPLDKVCLIGC * X_tropicalis -py-r-GlMlDnTNRFTCKGnpVytFLsTSTFTEYTVLDEicVAKIDdnAPLDKVCLIGC * Rat-ADH1 -qP-k-GaLlDGTSRFSCRGKpIHHFIsTSTFSQYTVVDDiAVAKIDAAAPLDKVCLIGC * Rat-Q8K571 -qP-k-GaLlDGTSRFSCRGKpIHHFIsTSTFSQYTVVDDiAVAKIDAAAPLDKVCLIGC * Struthio_camelus-ADH1 -pa-s-alMpDGTSRFTCKGKaIHHFaGTSTFTEYTVLHEtAVAKIDAAAPLEKVCLIGC * Struthio_camelus-ADH1_VAR -pa-s-alMpDGTSRFTCKGKaIHHFaGTSTFTEYTVLHEtAVAKIDAAAPLEKVCLIGC * Alligator_mississippiensis-ADH1 -sP-s-GlMaDGTSRFTCKGKdIHHFIGTSTFTEYTVVHEtAVARIDAAAPLEKVCLIGC * Alligator_mississippiensis-ADH1_VAR_1 -sP-s-GlMaDGTSRFTCKGKdIHHFIGTSTFTEYTVVHEtAVARIDAAAPLEKVCLIGC * Alligator_mississippiensis-ADH1_VAR_2 -sP-s-GlMaDGTSRFTCKGKdIHHFIGTSTFTEYTVVHEtAVARIDAAAPLEKVCLIGC ==================================================================================================== Consensus xxpxxxgxmxdgTSRFTCRGKxIhnFLgtSTFSQYTVVNExaVAKIDaaaPLEKVCLIGC 190 200 210 220 230 240 ----:----|----:----|----:----|----:----|----:----|----:----| Consensus GfSTGYGsAVkxAKVxpGSTCAVFGLGgVGLsvIMGCKaAGAxRIIaVDiNkEKFaKAKe ==================================================================================================== * GADUS_MORHUA GvSTGFGaAVntAKVePGSTCAVFGLGaVGLaaVMGChsAGAkRIIAVDLNpDKFeKAKv * Danio_rerio GiTTGYGaAVntAgVtPGSvCAVFGLGaVGLaaVMGCKnAGAsRIfAVDINEKKFeKAKv * Oryzias_latipes GvcTGFGaAVntAKVePGSTCAVFGLGaVGLaaVMGCKfAGAkRIfAVDtNpEKaeKARv ==================================================================================================== * HUMAN GFSTGYGSAVnvAKVtPGSTCAVFGLGGVGLSaIMGCKAAGAaRIIAVDINKDKFAKAKE * HORSE GFSTGYGSAVKvAKVtqGSTCAVFGLGGVGLSVIMGCKAAGAaRIIgVDINKDKFAKAKE * 1A71A_Horse GFSTGYGSAVKvAKVtqGSTCAVFGLGGaGLSVIMGCKAAGAaRIIgVDINKDKFAKAKE * 1AXEA_Horse GFSTGYGSAVKvAKVtqGSTCAVFGLGGVGLSVIMGCKAAGAaRIIgVDINKDKFAKAKE * 1AXGA_Horse GFSTGYGSAVKvAKVtqGSTCAVFGLGGaGLSVIMGCKAAGAaRIIgVDINKDKFAKAKE * 1JU9A_Horse GFSTGYGSAVKvAKVtqGSTCAVFGLGGVGLSVIMGCKAAGAaRIIgVDINKDKFAKAKE * 1MGOA_Horse GFSTGYGSAVKvAKVtqGSTCAVFGLGGVGLSVIMGCKAAGAaRIIgVDINKDKFAKAKE * 1N8KA_Horse GFSTGYGSAVKvAKVtqGSTCAVFGLGGVGLSVIMGCKAAGAaRIIgVDINKDKFAKAKE * 1QLHA_Horse GFSTGYGSAVKvAKVtqGSTCAVFGLGGVGLSVIMGCKAAGAaRIIgVDINKDKFAKAKE * 1QV6A_Horse GFSTGYGSAVKvAKVtqGSTCAVFGLGGVGLSVIMGCKAAGAaRIIgVDINKDRFAKAKE * Apteryx_australis GFSTGYGaAVQtAKVePGSTCAVFGLGGVGLSVVMGCKAAGAsRIIAIDINKDKFAKAKE * Canis_lupus GFSTGYGSAVnvAKVtPGSTCAVFGLGGVGLSVIMGCKAAGAaRIIgVDINKDKFAKAKE * Coturnix_coturnix GFSTGYGavLQtAKVePGSTCAVFGLGGVGLSVVMGCKAAGAsRIIAIDINKDKFAKAKE * Chicken GFSTGYGavLQtAKVeaGSTCAVFGLGGVGLSVVMGCKAAGAsRIIAVDINKDKFAKAKE * Macaca_mulatta GFSTGYGSAVKvAKVtPGSTCAVFGLGGVGLSaVMGCKAAGAaRIIAVDINKDKFAKAKE * Mouse GFSTGYGSAVKvAKVtPGSTCAVFGLGGVGLSVIIGCKAAGAaRIIAVDINKDKFAKAKE * Rabbit GFSTGYGSAVKvAKVtPGSTCAVFGLGGVGLSVIMGCKAAGAsRIIAVDINKDKFpKAKE * Pan_troglodytes GFSTGYGSAVnvAKVtPGSTCAVFGLGGVGLSaIMGCKAAGAaRIIAVDINKDKFAKAKE * Pongo_pygmaeus GFSTGYGSAVnvAKVtPGSTCAVFGLGGVGLSVVMGCKAAGAaRIIAVDINKDKFAKAKE * X_laevis GFSTGYGSAVKtAKVePGSSCAVFGLGGVGLSVLIGCKvAGAaKIIgVDtNpDKFAKAKE * X_tropicalis GFSTGYGSAVKiAKVeqGSSCAVFGLGGVGLSVLIGCKvAGAsKIIgVDtNsDKFAKAKE * Rat-ADH1 GFSTGYGSAVQvAKVtPGSTCAVFGLGGVGLSVVIGCKtAGAaKIIAVDINKDKFAKAKE * Rat-Q8K571 GFSTGYGSAVQvAKVtPGSTCAVFGLeGVGLSVVIGCKtAGAaKIIAVDINKDKFAKAKE * Struthio_camelus-ADH1 GFSTGYGaALQtAKVePGSTCAVFGLGGVGLSVVMGCKAAGAsRIIgVDINKDKFAKAKE * Struthio_camelus-ADH1_VAR GFSTGYGaALQtAKVePGSTCAVFGLGGVGLSVVMGCKAAGAsRIIgVDINKDKFAKAKE * Alligator_mississippiensis-ADH1 GFSTGYGaAVKdAKVePGSTCAVFGLGGVGLStIMGCKAAGAsRIIgIDINKDKFAKAKE * Alligator_mississippiensis-ADH1_VAR_1 GFSTGYGaAVKdAKVePGSTCAVFGLGGVGLStIMGCKAAGAsRIIgIDINKDKFAKAKE * Alligator_mississippiensis-ADH1_VAR_2 GFSTGYGaAVKtAKVePGSTCAVFGLGGVGLStIMGCKAAGAsRIIgIDINKDKFAKAKE ==================================================================================================== Consensus GfSTGYGsAVkxAKVxpGSTCAVFGLGgVGLsvIMGCKaAGAxRIIaVDiNkEKFaKAKe 250 260 270 280 290 300 ----:----|----:----|----:----|----:----|----:----|----:----| Consensus lGATEcVNPqDYxKPIxEVLxEMSnxgGVDFSfEvIGrlEtMxxaLxxChxxyGvSVIVG ==================================================================================================== * GADUS_MORHUA fGATDfVNPnDhsEPIsQVLsKMTN-GGVDFSlEcVGnVgvMrnALesClkgWGVSVLVG * Danio_rerio fGATDfLNPKaFnKPIsEVLiEMTNgGGVDFSiEctGntEvMrsALesCakgWGVSVVVG * Oryzias_latipes fGATDfVNPKDYnKPIsKVLaEMTN-GGVDYSlEcVGnVDvMrsALesCmkgWGVSVVVG ==================================================================================================== * HUMAN LGATECINPQDYkKPIqEVLkEMTD-GGVDFSFEVIGRLDTMmasLlcCHeacGtSVIVG * HORSE VGATECVNPQDYkKPIqEVLtEMSN-GGVDFSFEVIGRLDTMvtALscCqeaYGVSVIVG * 1A71A_Horse VGATECVNPQDYkKPIqEVLtEMSN-GGVDFSFEVIGRLDTMvtALscCqeaYGVSVIVG * 1AXEA_Horse VGATECVNPQDYkKPIqEVLtEMSN-GGVDFSFEVIGRLDTMvtALscCqeaYGVSVIVG * 1AXGA_Horse VGATECVNPQDYkKPIqEVLtEMSN-GGVDFSFEVIGRLDTMvtALscCqeaYGVSVIVG * 1JU9A_Horse VGATECVNPQDYkKPIqEVLtEMSN-GGVDFSFEVIGRLDTMvtALscCqeaYGVSVIsG * 1MGOA_Horse VGATECVNPQDYkKPIqEVLtEMSN-GGVDFSFEVIGRLDTMvtALscCqeaYGVSVIVG * 1N8KA_Horse VGATECVNPQDYkKPIqEVLtEMSN-GGVDFSFEVIGRLDTMvtALscCqeaYGVSVItG * 1QLHA_Horse VGATECVNPQDYkKPIqEVLtEMSN-GGVDFSFEVIGRLDTMvtALscCqeaYGVSVIVa * 1QV6A_Horse VGATECVNPQDYkKPIqEVLtEMSN-GGVDFSFEVIGRLDTMvtALscCqeaYGVSVIVG * Apteryx_australis LGATDCVNPKDFtKPIhEVLmEMTg-lGVDYSFEVIGhtETMaaALasCHfnYGVSVILG * Canis_lupus VGATECISPQDYkEPIqEVLkEISg-GsVDFSFEVIGRLDTMvaALscCqesYGVSVIVG * Coturnix_coturnix LGATECVNPKDFkKPIhEVLtEMTg-kGVDYSFEVIGRIETMteALasCHynYGVSVIVG * Chicken LGATECINPKDFkKPIhEVLtEMTg-qGVDYSFEVIGRIETMtaALasCHnnYGVSVIVG * Macaca_mulatta LGATECINPQDYkKPIqEVLkEMTD-GGVDFSFEVIGRLDTMmasLlcCHeacGtSVIVG * Mouse LGATECINPQDYsKPIqEVLqEMTD-GGVDFSFEVIGRLDTMtsALlsCHaacGVSVVVG * Rabbit VGATECINPQDYkKPIqEVIqEISD-GGVDFSFEVIGRLDTVvaALlsCHgacGtSVIVG * Pan_troglodytes LGATECINPQDYkKPIqEVLkEMTD-GGVDFSFEVIGRLDTMmasLlcCHeacGtSVIVG * Pongo_pygmaeus LGATECINPQDYnKPIqEVLkEMTD-GGVDFSFEVIGRLDTMmasLlcCHeacGtSVIVG * X_laevis LGATECINPnDYkEPIhEVLaKMSN-GGLDYTFEcIGntKvMesALlatHfgcGtSVIVG * X_tropicalis LGATECINPnDYnEPIhEVLaKISD-GGLDYTFEcIGntKvMesALkatHfgcGtSVIVG * Rat-ADH1 LGATDCINPQDYtKPIqEVLqEMTD-GGVDFSFEVIGRLDTMtsALlsCHsacGVSVIVG * Rat-Q8K571 LGATDCINPQDYtKPIqEVLqEMTD-GGVDFSFEVIGRLDTMtsALlsCHsacGVSVIVG * Struthio_camelus-ADH1 LGATDCVNPKDFtKPIhEVLmEMTg-lGVDYSFEVIGhtETMaaALasCHfnYGVSVIVG * Struthio_camelus-ADH1_VAR LGATDCVNPKDFtKPIhEVLmEMTg-lGVDYSFEVIGhtETMaaALasCHfnYGVSVIVG * Alligator_mississippiensis-ADH1 LGATECINPlDckKPIqEVLsEMTg-GGVDYSFEVIGRIDTMtaALacCqdnYGtSVIVG * Alligator_mississippiensis-ADH1_VAR_1 LGATECINPlDckKPIqEVLsEMTg-GGVDYSFEVIGRIDTMtaALacCqdnYGtSVIVG * Alligator_mississippiensis-ADH1_VAR_2 LGATECINPlDckKPIqEVLsEMTg-GGVDYSFEVIGRIDTMtaALacCqdnYGtSVIVG ==================================================================================================== Consensus lGATEcVNPqDYxKPIxEVLxEMSnxgGVDFSfEvIGrlEtMxxaLxxChxxyGvSVIVG 310 320 330 340 350 360 ----:----|----:----|----:----|----:----|----:----|----:----| Consensus vppnxqnLSmnPMlLlsGRTWKGaIfGGFKSKDxVPKLVaDFMaKKfxLDxlITHxLpfe ==================================================================================================== * GADUS_MORHUA wt-DlhDVatrPIqLIaGRTWKGsMFGGFKgKDgVPKMVkaYLdKKvkLDefITHrMPlE * Danio_rerio wt-NvQDfSakPIqLIyGKTWKGsLFGGFKcKDsVPKLVrDYMsgKimLDefITHkMnlE * Oryzias_latipes wt-DkhDfSarPIqLIaGRTWKGtLFGGFKSKDgVPQMVkaYMeRKvkLDefITHnMtlt ==================================================================================================== * HUMAN VPPDsQNLSMNPMLLLTGRTWKGAIlGGFKSKEcVPKLVADFMAKKFsLDaLITHvLPFE * HORSE VPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLITHvLPFE * 1A71A_Horse VPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLITHvLPFE * 1AXEA_Horse VPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLITHvLPFE * 1AXGA_Horse VPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLITHvLPFE * 1JU9A_Horse VPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLITHvLPFE * 1MGOA_Horse VPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLITHvLPFE * 1N8KA_Horse VPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLITHvLPFE * 1QLHA_Horse VtPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLITHvLPFE * 1QV6A_Horse VPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLITHvLPFE * Apteryx_australis VPPaaEkISfDPMLLfSGRTWKGsVFGGWKSKDaVPKLVADYMeKKFvLEpLITHtLPFi * Canis_lupus VPPNsQSLSMNPMLLLTGRSWKGAIFGGFKSKDsVPKLVADFMAKKFpLEsLITHvLPFE * Coturnix_coturnix VPPaaQkISfDPMLIfSGRTWKGsVFGGWKSKDaVPKLVADYMkKKFvLDpLITHtLPFt * Chicken VPPaaQkISfDPMLIfSGRTWKGsVFGGWKSKDaVPKLVADYMkKKFvLDpLITHtLPFt * Macaca_mulatta VPPDsQNLSINPMLLLTGRTWKGAVYGGFKSKEdIPKLVADFMAKKFsLDaLITHvLPFE * Mouse VPPNaQNLSMNPMLLLlGRTWKGAIFGGFKSKDsVPKLVADFMAKKFpLDpLITHvLPFE * Rabbit VPPDsQSLTVNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFsLDpLITNvLPFE * Pan_troglodytes VPPDsQNLSMNPMLLLTGRTWKGAIlGGFKSKEcVPKLVADFMAKKFsLDvLITHvLPFE * Pongo_pygmaeus VPPDsQNLSMNPMLLLTGRTWKGAVlGGFKSKEcVPKLVADFMAKKFsLDaLITHvLPFE * X_laevis LaPasarVlVDPMeMLTGRTlKGALFGGWKSRDdVPKLVADFMAKKFeLDgLITHrstlD * X_tropicalis LaPasarVSVDPMeMLTGRTlKGALFGGWKSRDeVPQLVADFLAKKFeLDgLITHrstlD * Rat-ADH1 VPPSaQSLSVNPMsLLlGRTWKGAIFGGFKSKDaVPKLVADFMAKKFpLEpLITHvLPFE * Rat-Q8K571 VPPSaQSLSVNPMsLLlGRTWKGAIFGGFKSKDaVPKLVADFMAKKFpLEpLITHvLPFE * Struthio_camelus-ADH1 VPPaaEkLSfDPMLLfSGRTWKGsVFGGWKSKDsVPKLVADYMeKKFvLDpLITHtLPFh * Struthio_camelus-ADH1_VAR VPPaaEkLSfDPMLLfSGRTWKGsVFGGWKSKDsVPKLVADYMeKKFvLDpLITHtLPFh * Alligator_mississippiensis-ADH1 VPPasEkITfNPMMLfTGRTWKGsVFGGWKSKEsVPKLVADYMeKKinLDgLITHtLPFD * Alligator_mississippiensis-ADH1_VAR_1 VPPasEkITfNPMMLfTGRTWKGtVFGGWKSKEsVPKLVADYMeKKinLDgLITHtLPFD * Alligator_mississippiensis-ADH1_VAR_2 VPPasEkITfNPMMLfTGRTWKGsVFGGWKSKEsVPKLVADYMeKKinLDgLITHtLPFD ==================================================================================================== Consensus vppnxqnLSmnPMlLlsGRTWKGaIfGGFKSKDxVPKLVaDFMaKKfxLDxlITHxLpfe 370 380 390 400 410 420 ----:----|----:----|----:----|----:----|----:----|----:----| Consensus KINEgfDLLRsGEsIRTILxfx ============================================================== * GADUS_MORHUA sVNDaiDLMKhGKcIRTVLsle * Danio_rerio QVNDaiNLMKTGQgIRTIMtvs * Oryzias_latipes QVNEaiELMKrGgcIRTVLsvs ============================================================== * HUMAN KINEGFDLLhSGKSIRTILmF- * HORSE KINEGFDLLRSGESIRTILtF- * 1A71A_Horse KINEGFDLLRSGESIRTILtF- * 1AXEA_Horse KINEGFDLLRSGESIRTILtF- * 1AXGA_Horse KINEGFDLLRSGESIRTILtF- * 1JU9A_Horse KINEGFDLLRSGESIRTILtF- * 1MGOA_Horse KINEGFDLLRSGESIRTILtF- * 1N8KA_Horse KINEGFDLLRSGESIRTILtF- * 1QLHA_Horse KINEGFDLLRSGESIRTILtF- * 1QV6A_Horse KINEGFDLLRSGESIRTILtF- * Apteryx_australis KINEGFDLLRkGKSIRSVLvF- * Canis_lupus KINEGFDLLRSGKSIRTVLtF- * Coturnix_coturnix KINEGFDLLRTGKSIRTVLvl- * Chicken KINEGFDLLRTGKSIRSVLvl- * Macaca_mulatta KINEGFDLLRSGKSIRTILtF- * Mouse KINEaFDLLRSGKSIRTVLtF- * Rabbit KINEGFDLLRSGKSIRTILtF- * Pan_troglodytes KINEGFDLLhSGKSIRTILmF- * Pongo_pygmaeus KINDGFDLLhSGKSIRTILmF- * X_laevis KINEGFDLLRkGDSIRTILqis * X_tropicalis KINEGFDLLRkGDSIRTILqis * Rat-ADH1 KINEaFDLLRaGKSIRTVLtF- * Rat-Q8K571 KINEaFDLLRaGKSIRTVLtF- * Struthio_camelus-ADH1 KINEGFDLLRTGKSIRSVLlF- * Struthio_camelus-ADH1_VAR KINEGFDLLRTGKSIRSVLlF- * Alligator_mississippiensis-ADH1 KINEGFELLRTGKSIRSVLtF- * Alligator_mississippiensis-ADH1_VAR_1 KINEGFELLRTGKSIRSVLtF- * Alligator_mississippiensis-ADH1_VAR_2 KINEGFELLRTGKSIRSVLtF- ============================================================== Consensus KINEgfDLLRsGEsIRTILxfx

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