100       110       120       130
                                  ----:----|----:----|----:----|----:----|----:
  Consensus                       xxxxxxxxxxxxxRQfxVxGNWKMNgnKxnLxELIxxLNxxxxxx
===============================================================================
* S_CEREVISIAE                    ------------aRtFfVgGNFKLNGSKqSIkEIVerLNt---as
* Candida_albicans                ------------aRQFfVgGNFKaNGtKqqItsIIdnLNk---ad
* Candida_glabrata                ------------aRtFfVgGNFKLNGtKkSIkEIVdrLNt---as
* Debaryomyces_hansenii           ------------aRQFfVgGNFKMNGtReSVsKIVdgLNk---ae
* Eremothecium_gossypii           ------------aRtFfVgGNFKLNGSKqSIkEIVerLNt---ad
* Yarrowia_lipolytica             ------------sRtFfVgGNFKMNGSleSIkaIVerLNa---se
* Zygosaccharomyces_bailii        ------------aRtFfVgGNFKLNGtKsSIkEIVerLNn---ak
* Kluyveromyces_lactis-TPIS       ------------aRtFfIgGNFKMNGSKaSIkEIVdrLNg---as
* Kluyveromyces_lactis-TPIS_KLUMA ------------aRtFfIgGNFKMNGtKaSIkEIVerLNs---as
===============================================================================
* C_ELEGANS                       ------------tRKFfVgGNWKMNGDyaSVdgIVtfLNa---sa
* HUMAN                           ----------apsRKFfVgGNWKMNGrKqSLgELIgtLNa---ak
* RABBIT                          ----------apsRKFfVgGNWKMNGrKkNLgELIttLNa---ak
* CHICKEN                         ----------ap-RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1SPQA_Chicken                   -------------RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1SPQB_Chicken                   ----------ap-RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1SQ7A_Chicken                   ----------ap-RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1SSDA_Chicken                   ----------ap-RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1SU5A_Chicken                   ----------ap-RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1SW3A_Chicken                   ----------ap-RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1SW7A_Chicken                   -------------RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1TPB1_Chicken                   -------------RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1TPC1_Chicken                   -------------RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1TPUA_Chicken                   -------------RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1TPVA_Chicken                   -------------RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1TPWA_Chicken                   -------------RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* Acipenser_brevirostrum          ----------aptRKFfVgGNWKLNGDKkSLgELIhtLNs---gk
* Anopheles_gambiae               -----------g-RKFcVgGNWKMNGDKaSItELcktLSa---gp
* Bovine                          ----------apsRKFfVgGNWKMNGrKnNLgELIntLNa---ak
* C_briggsae                      -----------a-RKFfVgGNWKMNGDfaSVdgIVafLNq---sa
* Canis_lupus                     ----------apsRKFfVgGNWKMNGrKkNLgELIttLNa---ak
* Danio_rerio                     ----------sg-RKFfVgGNWKMNGDKkSIeELantLNs---ak
* Gorilla_gorilla                 ----------apsRKFfVgGNWKMNGrKqSLgELIgtLNa---ak
* Latimeria_chalumnae             ----------ap-RKFfVgGNWKMNGDKkSLgELIqtLNa---ak
* Lepisosteus_osseus              --------------------------DKkvLgDLIntLNt---ak
* Macaca_mulatta                  ----------apsRKFfVgGNWKMNGrKqNLgELIgtLNa---ak
* Mouse                           ----------aptRKFfVgGNWKMNGrKkcLgELIctLNa---an
* Oryzias_latipes                 ----------aq-RRFfVgGNWKMNGNKeSLeELMstLNt---as
* Pongo_pygmaeus                  ----------apsRKFfVgGNWKMNGrKqSLgELIgtLNa---ak
* Schistosoma_mansoni             ---s------gs-RKFfVgGNWKMNGSRdDndKLLklLSe---ah
* Strongylocentrotus_purpuratus   ----------sg-RRFwVgGNYKMNGSKaSIdgLLkmLee---sq
* Pig                             ----------apaRKFfVgGNWKMNGrKnNLgELIntLNa---ak
* Tribolium_castaneum             cscs------mg-RKFvVgGNWKMNGDKkqIsEIIntLkt---gp
* X_laevis                        ----------sp-RKFfVgGNWKMNGDKkSLgELIntLNs---gk
* D_melanogaster-TPIS             tdctdsnsnnms-RKFcVgGNWKMNGDQkSIaEIaktLSs---aa
* D_melanogaster-TPIS_VAR         tdctdsnsnnms-RKFcVgGNWKMNGDQkSIaEIaktLSs---aa
* Rat-Q6P793                      ----------apsRKFfVgGNWKMNGrKkcLgELIctLNa---ak
* Rat-TPIS                        ----------apsRKFfVgGNWKMNGrKkcLgELIctLNa---ak
===============================================================================
  ENTAMOEBA_HISTOLYTICA           -----------gagKFvVgGNWKcNGtlaSIetLtkgVaasvdae
===============================================================================
  LEISHMANIA_MEXICANA             ----------sakpQpiaaaNWKcNGttaSIeKLVqvfNe---ht
  TRYPANOSOMA_CRUZI               ----------askpQpiaaaNWKcNGSEslLvpLIetLNa---at
  TRYPANOSOMA_BRUCEI              -----------skpQpiaaaNWKcNGSQqSLsELIdlfNs---ts
  1KV5A_Trypanosoma_brucei        -----------skpQpiaaaNWKcNGSQqSLsELIdlfNs---ts
  1MSSA_Trypanosoma_brucei        -----------skpQpiaaaNWKcNGSQqSLsELIdlfNs---ts
  1TRI0_Trypanosoma_brucei        -----------skpQpiaaaNW---GSQqSLsELIdlfNs---ts
  1TTI0_Trypanosoma_brucei        -----------skpQpiaaaNWK------SLsELIdlfNs---ts
  1TTJ0_Trypanosoma_brucei        -----------skpQpiaaaNW-------SLsELIdlfNs---ts
  Leishmania_donovani             ----------sskpQpiaaaNWKcNGttaSIeKLVqvLNe---hn
  Leishmania_tropica              ----------sakpQpiaaaNWKcNGttaSIeKLVqvLNe---hn
===============================================================================
  PLASMODIUM_FALCIPARUM           ------------aRKYfVaaNWKcNGtleSIksLtnsfNn--ldf
  1VGAB_Plasmodium_falciparum     -------------RKYfVaaNWKcNGtleSIksLtnsfNn--ldf
  Plasmodium_berghei              ------------aRKYfVsaNWKcNGtEySIksLadsfNt--vdf
  Plasmodium_chabaudi             ------------aRKYfVsaNWKcNGtKdSIktLadsfNt--vdf
===============================================================================
B E_COLI                          -------------RhplVmGNWKLNGSRhmVhELVsnLrk--ela
B VIBRIO_MARINUS                  -------------RhpvVmGNWKLNGSKemVvDLLngLNa--ele
B Actinobacillus_pleuropneumoniae -----------a-RRplVmGNWKLNGSKaftkELIagLka--ela
B Actinobacillus_succinogenes     ----------as-RKplVmGNWKLNGSKaftrELIegLkt--ela
B Erwinia_carotovora              -------------RhplVmGNWKLNGStnlVnELIagLrk--els
B Haemophilus_ducreyi             -----------a-RRplVmGNWKLNGSKaftqQLIaeLkt--ela
B Haemophilus_influenzae          -----------a-RRplVmGNWKLNGSKaftkELIegLka--elh
B Histophilus_somni               -----------a-RRplVmGNWKLNGSKaftkELItgLkd--eln
B Mannheimia_succiniciproducens   -----------a-RRplVmGNWKLNGSKaftkELIegLka--ela
B Pasteurella_multocida           -----------a-RRplVmGNWKLNGSKaftkaLIedLkt--ela
B Photobacterium_profundum        -------iwrktmRhpvVmGNWKLNGSKemVvnLLngLNa--ele
B Photorhabdus_luminescens        -------------RhplVmGNWKLNGSthmVnELItgLrq--els
B Vibrio_cholerae                 -------------RRpvVmGNWKLNGSKamVtDLLngLNa--ele
B Vibrio_fischeri                 -------------RhpvVmGNWKLNGSKemVvELLngLNa--ele
B Vibrio_parahaemolyticus         -------------RRpvVmGNWKLNGSKamVtELLtgLNa--ele
B Vibrio_vulnificus               -------------RRpvVmGNWKLNGSKtmVaELLtgLNa--ele
B Yersinia_pestis                 -------------RhplVmGNWKLNGSthmVnELIagLrk--els
B Salmonella_typhi-TPIS           -------------RhplVmGNWKLNGSRhmVnELVanLrk--elt
B Salmonella_typhi-TPIS_SALTY     -------------RhplVmGNWKLNGSRhmVnELVanLrk--elt
===============================================================================
B THERMUS_AQUATICUS               -------------RRvlVaGNWKMHktpsearvwfaeLkr---ll
===============================================================================
B BACILLUS_STEAROTHERMOPHILUS     -------------RKpiIaGNWKMHktlaeavQfVedVkg--hvp
B Bacillus_clausii                -------------RKpiIaGNWKMNktigeavDfVeaVka--nvp
B Bacillus_halodurans             -------------RKpiIaGNWKMNktvgeakafVeeVkg--aip
B Bacillus_licheniformis          -------------RKpiIaGNWKMNkvlseavsfVeeVks--sip
B Bacillus_megaterium             -------------RKpiIaGNWKMNkvlseatsfVeeVkg--avp
B Bacillus_subtilis               -------------RKpiIaGNWKMNktlgeavsfVeeVks--sip
B Listeria_monocytogenes-TPIS1    -------------RKpiIaGNWKMNktaakagQfaedVkn--nvp
B Listeria_monocytogenes-TPIS1_LI -------------RKpiIaGNWKMNktaakagQfaedVkn--nvp
===============================================================================
  Consensus                       xxxxxxxxxxxxxRQfxVxGNWKMNgnKxnLxELIxxLNxxxxxx