ADH1

10 20 30 40 50 60 70 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus STAGKVIKCKAAVlWExkKPFSIEEVEVAPPQAhEVRIKMVAtGICrSDDHvVsGxLxvxPlPvILGHEa ================================================================================================= GADUS_MORHUA aTvGKVIKCKAAVaWEanKPlvIEEIEVdvPhANEIRIKIIATGVChTDlyhLfegkhkdgfPVVLGHEg Danio_rerio aTAGKVIKCRAAVaWEpKaPlmMEEIEVAPPQegEIRIKVIATGLChTDlyhLvdg-dkrgfPVVLGHEs Oryzias_latipes aTAGKVIKCKAAVaWEpnKPlvIEDIEVAPPQANEVRIKIVATGVChTDlyhLfegMhkdgfPaVLGHEg ================================================================================================= HORSE STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtL-VtPLPVIaGHEA HUMAN STAGKVIKCKAAVLWEvKKPFSIEDVEVAPPKAyEVRIKMVAvGICRTDDHVVSGnL-VtPLPVILGHEA 1A71A_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtL-VtPLPVIaGHEA 1AXEA_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtL-VtPLPVIaGHEA 1AXGA_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtL-VtPLPVIaGHEA 1JU9A_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtL-VtPLPVIaGHEA 1MGOA_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtL-VtPLPVIaGHEA 1N8KA_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtL-VtPLPVIaGHEA 1QLHA_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGtL-VtPLPVIaGHEA 1QV6A_Horse STAGKVIKCKAAVLWEeKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDqVVSGtL-VtPLPVIaGHEA 1HDYA_Human STAGKVIKCKAAVLWEvKKPFSIEDVEVAPPKAyEVRIKMVAvGIChTDDHVVSGnL-VtPLPVILGHEA 1HDZA_Human STAGKVIKCKAAVLWEvKKPFSIEDVEVAPPKAyEVRIKMVAvGICgTDDHVVSGnL-VtPLPVILGHEA 1HSOA_Human STAGKVIKCKAAVLWElKKPFSIEEVEVAPPKAHEVRIKMVAvGICgTDDHVVSGtM-VtPLPVILGHEA 1HTBA_Human STAGKVIKCKAAVLWEvKKPFSIEDVEVAPPKAyEVRIKMVAvGICRTDDHVVSGnL-VtPLPVILGHEA Alligator_mississippiensis STAGKVIKCKAAItWEiKKPFSIEEIEVAPPKAHEVRIKILATGICRSDDHVtaGlL-tmPLPMILGHEA Apteryx_australis STAGKVIKCKAAVLWEpKKPFSIEEVEVAPPKAHEVRIKILATGICRSDDHVITGaL-VrPfPIILGHEA Canis_lupus STAGKVIKCKAAVLWElKKPFSIEEVEVAPPKAHEVRIKMVASGICRSDDHVVTGaL-VvPLPIILGHEA Coturnix_coturnix STAGKVIKCKAAVLWEanKPFSLEEVEVAPPKAHEVRIKIVATGICRSDDHVVTGaL-amPfPVILGHEA Gallus_gallus STvGKVIKCKAAVLWEanKPFSLEEVEVAPPKAHEVRIKIVATGICRSDDHVVTGaL-amPfPIILGHEA Macaca_mulatta STAGKVIKCKAAVLWEvmKPFSIEDVEVAPPKAyEVRIKMVtvGICgTDDHVVSGtM-VtPLPVILGHEA Mus_musculus STAGKVIKCKAAVLWElhKPFTIEDIEVAPPKAHEVRIKMVATGVCRSDDHVVSGtL-VtPLPaVLGHEg Oryctolagus_cuniculus STAGKVIKCKAAVLWQlnKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHaVTGsI-avPLPVILGHEA Pan_troglodytes STAGKVIKCKAAVLWEvKKPFSIEDVEVAPPKAyEVRIKMVAvGICRTDDHVVSGnL-VtPLPaILGHEA Papio_hamadryas STAGKVIKCKAAVLWEvKKPFSIEDVEVAPPKAyEVRIKMVAvGICRTDDHVVSGnL-VsPLPaILGHEA Pongo_pygmaeus STAGKVIKCKAAVLWElKKPFSIEEVEVAPPKAqEVRIKMVAvGICgTDDHVVSGtM-VtPLPaILGHEA Rattus_norvegicus STAGKVIKCKAAVLWEphKPFTIEDIEVAPPKAHEVRIKMVATGVCRSDDHaVSGsL-ftPLPaVLGHEg Struthio_camelus STAGKVIKCKAAVLWEpKKPFSIEEVEVAPPKAHEVRVKIIATGICRSDDHVISGvL-VmPfPIILGHEA ================================================================================================= Consensus STAGKVIKCKAAVlWExkKPFSIEEVEVAPPQAhEVRIKMVAtGICrSDDHvVsGxLxvxPlPvILGHEa 80 90 100 110 120 130 140 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus AGIVESIGEGVTslKPGDKVIPLWiPQCGKCkiCkNpExNxClKxNDLxsnpqgxmxdgTsRFTCRGKxI ================================================================================================= GADUS_MORHUA AGIVESVGpGVTefQPGEKVIPLFIsQCGECRfCQSPKtNqCVK-gwa-NespdvMspkeTRFTCKGRkV Danio_rerio AGVVESVGpGVTdyKPGDKVIPLFLsQCGKCKfCKcPKtNlCes-Swa-TkyhdiMaEpTSRFTCRGQtI Oryzias_latipes AGIVESVGpGVSefQPGDRVIPLFIsQCrECRfCKSPKtNqCeK-gwa-aDhydvMaladSRFTCKGKkV ================================================================================================= HORSE AGIVESIGEGVTTVRPGDKVIPLFtPQCGKCRVCKHPEgNfCLK-NDL-SmPRGtMqDGTSRFTCRGKpI HUMAN AGIVESVGEGVTTVKPGDKVIPLFtPQCGKCRVCKNPEsNyCLK-NDL-gNPRGtLqDGTrRFTCRGKpI 1A71A_Horse AGIVESIGEGVTTVRPGDKVIPLWtPQCGKCRVCKHPEgNfCLK-NDL-SmPRGtMqDGTSRFTCRGKpI 1AXEA_Horse AGIVESIGEGVTTVRPGDKVIPLWtPQCGKCRVCKHPEgNfCLK-NDL-SmPRGtMqDGTSRFTCRGKpI 1AXGA_Horse AGIVESIGEGVTTVRPGDKVIPLFtPQCGKCRVCKHPEgNfCLK-NDL-SmPRGtMqDGTSRFTCRGKpI 1JU9A_Horse AGIVESIGEGVTTVRPGDKVIPLFtPQCGKCRVCKHPEgNfCLK-NDL-SmPRGtMqDGTSRFTCRGKpI 1MGOA_Horse AGIVESIGEGVTTVRPGDKVIPLatPQCGKCRVCKHPEgNfCLK-NDL-SmPRGtMqDGTSRFTCRGKpI 1N8KA_Horse AGIVESIGEGVTTVRPGDKVIPLFtPQCGKCRVCKHPEgNfCLK-NDL-SmPRGtMqDGTSRFTCRGKpI 1QLHA_Horse AGIVESIGEGVTTVRPGDKVIPLFtPQCGKCRVCKHPEgNfCLK-NDL-SmPRGtMqDGTSRFTCRGKpI 1QV6A_Horse AGIVESIGEGVTTVRPGDKVIPLFtPQCGKCRVCKHPEgNfCLK-NDL-SmPRGtMqDGTSRFTCRGKpI 1HDYA_Human AGIVESVGEGVTTVKPGDKVIPLFtPQCGKCRVCKNPEsNyCLK-NDL-gNPRGtLqDGTrRFTCRGKpI 1HDZA_Human AGIVESVGEGVTTVKPGDKVIPLFtPQCGKCRVCKNPEsNyCLK-NDL-gNPRGtLqDGTrRFTCRGKpI 1HSOA_Human AGIVESVGEGVTTVKPGDKVIPLaIPQCGKCRICKNPEsNyCLK-NDV-SNPQGtLqDGTSRFTCRrKpI 1HTBA_Human AGIVESVGEGVTTVKPGDKVIPLFtPQCGKCRVCKNPEsNyCLK-NDL-gNPRGtLqDGTrRFTCRGKpI Alligator_mississippiensis AGVVEStGEGVTSLKPGDKVIPLFVPQCGECmpClksngNlCIR-NDL-gSPsGlMaDGTSRFTCKGKdI Apteryx_australis AGVVESVGEGVTSVKPGDKVIPLFVPQCGECsaClStKgNlCsK-NDI-gSasGlMpDGTTRFTCKGKaI Canis_lupus AGIVESIGEGVTTVKPGDKVIPLFtPQCGKCnVCKHPQgNlCVK-NDL-SkPRGtLqDGTiRFTCRGKpI Coturnix_coturnix AGVVESVGEkVTlLKPGDaVIPLFVPQCGECRsClStKgNlCIK-NDLsSSPtGlMaDGTTRFTCKGKaI Gallus_gallus AGVIESVGEkVTSLKPGDaVIPLFVPQCGECRsClStKgNlCIK-NDLsSSPtGlMaDGTTRFTCKGKaI Macaca_mulatta AGIVESVGEGVTTVEPGDKVIPLaLPQCGKCRICKtPErNyCLK-NDV-SNPRGtLqDGTSRFTCRGKpI Mus_musculus AGIVESVGEGVTcVKPGDKVIPLFsPQCGECRICKHPEsNfCsR-SDL-lmPRGtLrEGTSRFSCKGKqI Oryctolagus_cuniculus AGIVESIGEGVTTVKPGDKVIPLFtPQCGKCRICKHPEsNfCLi-NDL-gkPKGmLlDGTSRFTCKGKpI Pan_troglodytes AGIVESVGEGVTTVKPGDKVIPLFtPQCGKCRVCKNPEsNyCLK-NDL-gNPRGtLqDGTrRFTCRGKpI Papio_hamadryas AGIVESVGEGVTTVKPGDKVIPLFtPQCGKCRVCKSPEgNyCVK-NDL-SNPRGtLqDGTrRFTCRGKpI Pongo_pygmaeus AGIVESVGEGVTTVKPGDKVIPLaVPQCGKCRICKNPEsNyCLK-NDV-SNPQGtLqDGTSRFTCRGKpI Rattus_norvegicus AGIVESIGEGVTcVKPGDKVIPLFsPQCGKCRICKHPEsNlCcQtkNL-TqPKGaLlDGTSRFSCRGKpI Struthio_camelus AGVVESVGEGVTSVKPGDKVIPLFVPQCGECsVClStKgNlCrK-NDI-gpasalMpDGTSRFTCKGKaI ================================================================================================= Consensus AGIVESIGEGVTslKPGDKVIPLWiPQCGKCkiCkNpExNxClKxNDLxsnpqgxmxdgTsRFTCRGKxI 150 160 170 180 190 200 210 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus hHFLGtSTFSQYTVVNExAVAKIDaAaPLEKVCLIGCGFSTGYGsAVkvAKVtPGSTCAVFGLGGVGLSv ================================================================================================= GADUS_MORHUA lqFLGTSTFSQYTVVNQiAVAKIDpsAPLDtVCLLGCGvSTGFGaAVntAKVePGSTCAVFGLGaVGLaa Danio_rerio lqFMGTSTFSEYTVINQnAVAKIDenAPLDRVfLLGCGiTTGYGaAVntAgVTPGSvCAVFGLGaVGLaa Oryzias_latipes lqFMGaSTFSEYTVMNQiAVAKIDpAAPLDKVCLLGCGvcTGFGaAVntAKVePGSTCAVFGLGaVGLaa ================================================================================================= HORSE HHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGCGFSTGYGSAVKVAKVTqGSTCAVFGLGGVGLSV HUMAN HHFLGTSTFSQYTVVDEnAVAKIDAAsPLEKVCLIGCGFSTGYGSAVnVAKVTPGSTCAVFGLGGVGLSa 1A71A_Horse HHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGCGFSTGYGSAVKVAKVTqGSTCAVFGLGGaGLSV 1AXEA_Horse HHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGCGFSTGYGSAVKVAKVTqGSTCAVFGLGGVGLSV 1AXGA_Horse HHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGCGFSTGYGSAVKVAKVTqGSTCAVFGLGGaGLSV 1JU9A_Horse HHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGCGFSTGYGSAVKVAKVTqGSTCAVFGLGGVGLSV 1MGOA_Horse HHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGCGFSTGYGSAVKVAKVTqGSTCAVFGLGGVGLSV 1N8KA_Horse HHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGCGFSTGYGSAVKVAKVTqGSTCAVFGLGGVGLSV 1QLHA_Horse HHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGCGFSTGYGSAVKVAKVTqGSTCAVFGLGGVGLSV 1QV6A_Horse HHFLGTSTFSQYTVVDEisVAKIDAAsPLEKVCLIGCGFSTGYGSAVKVAKVTqGSTCAVFGLGGVGLSV 1HDYA_Human HHFLGTSTFSQYTVVDEnAVAKIDAAsPLEKVCLIGCGFSTGYGSAVnVAKVTPGSTCAVFGLGGVGLSa 1HDZA_Human HHFLGTSTFSQYTVVDEnAVAKIDAAsPLEKVCLIGCGFSTGYGSAVnVAKVTPGSTCAVFGLGGVGLSa 1HSOA_Human HHFLGiSTFSQYTVVDEnAVAKIDAAsPLEKVCLIGCGFSTGYGSAVnVAKVTPGSTCAVFGLGGVGLSa 1HTBA_Human HHFLGTSTFSQYTVVDEnAVAKIDAAsPLEKVCLIGCGFSTGYGSAVnVAKVTPGSTCAVFGLGGVGLSa Alligator_mississippiensis HHFIGTSTFTEYTVVHEtAVARIDAAAPLEKVCLIGCGFSTGYGaAVKdAKVePGSTCAVFGLGGVGLSt Apteryx_australis HHFIGTSTFTEYTVVHEtAVAKIaAAAPLEKVCLIGCGFSTGYGaAVQtAKVePGSTCAVFGLGGVGLSV Canis_lupus yHFLGiSTFSQYTVVDEfsVAKIDAAsPLEKVCLIGCGFSTGYGSAVnVAKVTPGSTCAVFGLGGVGLSV Coturnix_coturnix HHFIGTSTFTEYTVVHEtAaAKIDsAAPLEKVCLIGCGFSTGYGavLQtAKVePGSTCAVFGLGGVGLSV Gallus_gallus HHFVGTSTFTEYTVVHEtAaAKIDsAAPLEKVCLIGCGFSTGYGavLQtAKVeaGSTCAVFGLGGVGLSV Macaca_mulatta HHFLGvSTFSQYTVVDEnAVAKIDAAsPMEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSa Mus_musculus HNFIsTSTFSQYTVVDDiAVAKIDgAsPLDKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSV Oryctolagus_cuniculus HHFIGTSTFSQYTVVDEiAVAKIDAAAPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSV Pan_troglodytes HHFLGTSTFSQYTVVDEnAVAKIDAAsPLEKVCLIGCGFSTGYGSAVnVAKVTPGSTCAVFGLGGVGLSa Papio_hamadryas HHFVGTSTFSQYTVVDEnAVAKIDAAsPLEKVCLIGCGFSTGYGSAVnVAKVTPGSvCAVFGLGGVGLSa Pongo_pygmaeus HHFLGiSTFSQYTVVDEnAVAKIDAAsPLaKVCLIGCGFSTGYGSAVnVAKVTPGSTCAVFGLGGVGLSV Rattus_norvegicus HHFIsTSTFSQYTVVDDiAVAKIDAAAPLDKVCLIGCGFSTGYGSAVQVAKVTPGSTCAVFGLGGVGLSV Struthio_camelus HHFaGTSTFTEYTVLHEtAVAKIDAAAPLEKVCLIGCGFSTGYGaALQtAKVePGSTCAVFGLGGVGLSV ================================================================================================= Consensus hHFLGtSTFSQYTVVNExAVAKIDaAaPLEKVCLIGCGFSTGYGsAVkvAKVtPGSTCAVFGLGGVGLSv 220 230 240 250 260 270 280 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus IMGCKaAGAxRIIaVDINKEKFaKAKELGATECVNPQDYxKPIqEVLxEMSnxgGVDFSFEVIGrLDTMx ================================================================================================= GADUS_MORHUA VMGChsAGAkRIIAVDLNpDKFeKAKvfGATDfVNPnDhsEPIsQVLsKMTN-GGVDFSlEcVGnVgvMr Danio_rerio VMGCKnAGAsRIfAVDINEKKFeKAKvfGATDfLNPKaYnKPIsEVLiEMTNgGGVDFSiEctGntEvMr Oryzias_latipes VMGCKfAGAkRIfAVDtNpEKaeKARvfGATDfVNPKDYnKPIsKVLaEMTN-GGVDYSlEcVGnVDvMr ================================================================================================= HORSE IMGCKAAGAaRIIgVDINKDKFAKAKEVGATECVNPQDYkKPIQEVLtEMSN-GGVDFSFEVIGRLDTMv HUMAN VMGCKAAGAaRIIAVDINKDKFAKAKELGATECINPQDYkKPIQEVLkEMTD-GGVDFSFEVIGRLDTMm 1A71A_Horse IMGCKAAGAaRIIgVDINKDKFAKAKEVGATECVNPQDYkKPIQEVLtEMSN-GGVDFSFEVIGRLDTMv 1AXEA_Horse IMGCKAAGAaRIIgVDINKDKFAKAKEVGATECVNPQDYkKPIQEVLtEMSN-GGVDFSFEVIGRLDTMv 1AXGA_Horse IMGCKAAGAaRIIgVDINKDKFAKAKEVGATECVNPQDYkKPIQEVLtEMSN-GGVDFSFEVIGRLDTMv 1JU9A_Horse IMGCKAAGAaRIIgVDINKDKFAKAKEVGATECVNPQDYkKPIQEVLtEMSN-GGVDFSFEVIGRLDTMv 1MGOA_Horse IMGCKAAGAaRIIgVDINKDKFAKAKEVGATECVNPQDYkKPIQEVLtEMSN-GGVDFSFEVIGRLDTMv 1N8KA_Horse IMGCKAAGAaRIIgVDINKDKFAKAKEVGATECVNPQDYkKPIQEVLtEMSN-GGVDFSFEVIGRLDTMv 1QLHA_Horse IMGCKAAGAaRIIgVDINKDKFAKAKEVGATECVNPQDYkKPIQEVLtEMSN-GGVDFSFEVIGRLDTMv 1QV6A_Horse IMGCKAAGAaRIIgVDINKDRFAKAKEVGATECVNPQDYkKPIQEVLtEMSN-GGVDFSFEVIGRLDTMv 1HDYA_Human VMGCKAAGAaRIIAVDINKDKFAKAKELGATECINPQDYkKPIQEVLkEMTD-GGVDFSFEVIGRLDTMm 1HDZA_Human VMGCKAAGAaRIIAVDINKDKFAKAKELGATECINPQDYkKPIQEVLkEMTD-GGVDFSFEVIGRLDTMm 1HSOA_Human IMGCKAAGAaRIIAVDINKDKFAKAKELGATECINPQDYkKPIQEVLkEMTD-GGVDFSFEVIGRLDTMm 1HTBA_Human VMGCKAAGAaRIIAVDINKDKFAKAKELGATECINPQDYkKPIQEVLkEMTD-GGVDFSFEVIGRLDTMm Alligator_mississippiensis IMGCKAAGAsRIIgIDINKDKFAKAKELGATECINPlDckKPIQEVLsEMTg-GGVDYSFEVIGRIDTMt Apteryx_australis VMGCKAAGAsRIIAIDINKDKFAKAKELGATDCVNPKDFtKPIhEVLmEMTg-lGVDYSFEVIGhtETMa Canis_lupus IMGCKAAGAaRIIgVDINKDKFAKAKEVGATECISPQDYkEPIQEVLkEISg-GsVDFSFEVIGRLDTMv Coturnix_coturnix VMGCKAAGAsRIIAIDINKDKFAKAKELGATECVNPKDFkKPIhEVLtEMTg-kGVDYSFEVIGRIETMt Gallus_gallus VMGCKAAGAsRIIAVDINKDKFAKAKELGATECINPKDFkKPIhEVLtEMTg-qGVDYSFEVIGRIETMt Macaca_mulatta VMGCKAAGAaRIIAVDINKDKFAKAKELGATECINPQDYkKPIQEVLkEMTD-GGVDFSFEVIGRLDTMm Mus_musculus IIGCKAAGAaRIIAVDINKDKFAKAKELGATECINPQDYsKPIQEVLqEMTD-GGVDFSFEVIGRLDTMt Oryctolagus_cuniculus IMGCKAAGAsRIIAVDINKDKFpKAKEVGATECINPQDYkKPIQEVIqEISD-GGVDFSFEVIGRLDTVv Pan_troglodytes VMGCKAAGAaRIIAVDINKDKFAKAKELGATECINPQDYkKPIQEVLkEMTD-GGVDFSFEVIGRLDTMm Papio_hamadryas VMGCKAAGAaRIIAVDINKDKFAKAKELGATECINPQDYkKPIQEVLkEMTD-GGVDFSFEVIGRLDTMm Pongo_pygmaeus VMGCKAAGAaRIIAVDINKDKFAKAKELGATECINPQDYnKPIQEVLkEMTD-GGVDFSFEVIGRLDTMm Rattus_norvegicus VIGCKtAGAaKIIAVDINKDKFAKAKELGATDCINPQDYtKPIQEVLqEMTD-GGVDFSFEVIGRLDTMt Struthio_camelus VMGCKAAGAsRIIgVDINKDKFAKAKELGATDCVNPKDFtKPIhEVLmEMTg-lGVDYSFEVIGhtETMa ================================================================================================= Consensus IMGCKaAGAxRIIaVDINKEKFaKAKELGATECVNPQDYxKPIqEVLxEMSnxgGVDFSFEVIGrLDTMx 290 300 310 320 330 340 350 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus aaLxsChexyGvSVIVGVppnxQnLSmNPMlLlsGRTWKGaIFGGFKSKDxVPKLVADFMaKKfxLDxLI ================================================================================================= GADUS_MORHUA nALeSClKgWGVSVLVGwt-DlhDVatrPIqLIaGRTWKGsMFGGFKgKDgVPKMVkaYLdKKvkLDefI Danio_rerio sALeSCaKgWGVSVVVGwt-NvQDfSakPIqLIyGKTWKGsLFGGFKcKDsVPKLVrDYMsgKimLDefI Oryzias_latipes sALeSCmKgWGVSVVVGwt-DkhDfSarPIqLIaGRTWKGtLFGGFKSKDgVPQMVkaYMeRKvkLDefI ================================================================================================= HORSE tALscCqEaYGVSVIVGVPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLI HUMAN AsLlcCHEacGtSVIVGVPPasQNLSINPMLLLTGRTWKGAVYGGFKSKEgIPKLVADFMAKKFsLDaLI 1A71A_Horse tALscCqEaYGVSVIVGVPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLI 1AXEA_Horse tALscCqEaYGVSVIVGVPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLI 1AXGA_Horse tALscCqEaYGVSVIVGVPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLI 1JU9A_Horse tALscCqEaYGVSVIsGVPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLI 1MGOA_Horse tALscCqEaYGVSVIVGVPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLI 1N8KA_Horse tALscCqEaYGVSVItGVPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLI 1QLHA_Horse tALscCqEaYGVSVIVaVtPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLI 1QV6A_Horse tALscCqEaYGVSVIVGVPPDsQNLSMNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFaLDpLI 1HDYA_Human AsLlcCHEacGtSVIVGVPPasQNLSINPMLLLTGRTWKGAVYGGFKSKEgIPKLVADFMAKKFsLDaLI 1HDZA_Human AsLlcCHEacGtSVIVGVPPasQNLSINPMLLLTGRTWKGAVYGGFKSKEgIPKLVADFMAKKFsLDaLI 1HSOA_Human AsLlcCHEacGtSVIVGVPPDsQNLSMNPMLLLTGRTWKGAIlGGFKSKEcVPKLVADFMAKKFsLDaLI 1HTBA_Human AsLlcCHEacGtSVIVGVPPasQNLSINPMLLLTGRTWKGAVYGGFKSKEgIPKLVADFMAKKFsLDaLI Alligator_mississippiensis AALacCqDnYGtSVIVGVPPasEkITfNPMMLfTGRTWKGsVFGGWKSKEsVPKLVADYMeKKinLDgLI Apteryx_australis AALaSCHfnYGVSVILGVPPaaEkISfDPMLLfSGRTWKGsVFGGWKSKDaVPKLVADYMeKKFvLEpLI Canis_lupus AALscCqEsYGVSVIVGVPPNsQSLSMNPMLLLTGRSWKGAIFGGFKSKDsVPKLVADFMAKKFpLEsLI Coturnix_coturnix eALaSCHynYGVSVIVGVPPaaQkISfDPMLIfSGRTWKGsVFGGWKSKDaVPKLVADYMkKKFvLDpLI Gallus_gallus AALaSCHnnYGVSVIVGVPPaaQkISfDPMLIfSGRTWKGsVFGGWKSKDaVPKLVADYMkKKFvLDpLI Macaca_mulatta AsLlcCHEacGtSVIVGVPPDsQNLSINPMLLLTGRTWKGAVYGGFKSKEdIPKLVADFMAKKFsLDaLI Mus_musculus sALlSCHaacGVSVVVGVPPNaQNLSMNPMLLLlGRTWKGAIFGGFKSKDsVPKLVADFMAKKFpLDpLI Oryctolagus_cuniculus AALlSCHgacGtSVIVGVPPDsQSLTVNPMLLLSGRTWKGAIFGGFKSKDsVPKLVADFMAKKFsLDpLI Pan_troglodytes AsLlcCHEacGtSVIVGVPPasQNLSINPMLLLTGRTWKGAVYGGFKSKEgIPKLVADFMAKKFsLDaLI Papio_hamadryas AsLlcCHEacGtSVIVGVPPDsQNLSINPMLLLTGRTWKGAVYGGFKSREgIPKLVADFMAKKFsLDaLI Pongo_pygmaeus AsLlcCHEacGtSVIVGVPPDsQNLSMNPMLLLTGRTWKGAVlGGFKSKEcVPKLVADFMAKKFsLDaLI Rattus_norvegicus sALlSCHsacGVSVIVGVPPSaQSLSVNPMsLLlGRTWKGAIFGGFKSKDaVPKLVADFMAKKFpLEpLI Struthio_camelus AALaSCHfnYGVSVIVGVPPaaEkLSfDPMLLfSGRTWKGsVFGGWKSKDsVPKLVADYMeKKFvLDpLI ================================================================================================= Consensus aaLxsChexyGvSVIVGVppnxQnLSmNPMlLlsGRTWKGaIFGGFKSKDxVPKLVADFMaKKfxLDxLI 360 370 380 390 400 410 420 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus THvLPFeKINEgFDLLRsGESIRTILtfx ======================================================== GADUS_MORHUA THrMPlEsVNDaiDLMKhGKcIRTVLSle Danio_rerio THkMnlEQVNDaiNLMKTGQgIRTIMTvs Oryzias_latipes THnMtltQVNEaiELMKrGgcIRTVLSvs ======================================================== HORSE THVLPFEKINEGFDLLRSGESIRTILTF- HUMAN THVLPFEKINEGFDLLhSGKSIRTVLTF- 1A71A_Horse THVLPFEKINEGFDLLRSGESIRTILTF- 1AXEA_Horse THVLPFEKINEGFDLLRSGESIRTILTF- 1AXGA_Horse THVLPFEKINEGFDLLRSGESIRTILTF- 1JU9A_Horse THVLPFEKINEGFDLLRSGESIRTILTF- 1MGOA_Horse THVLPFEKINEGFDLLRSGESIRTILTF- 1N8KA_Horse THVLPFEKINEGFDLLRSGESIRTILTF- 1QLHA_Horse THVLPFEKINEGFDLLRSGESIRTILTF- 1QV6A_Horse THVLPFEKINEGFDLLRSGESIRTILTF- 1HDYA_Human THVLPFEKINEGFDLLhSGKSIRTVLTF- 1HDZA_Human THVLPFEKINEGFDLLhSGKSIRTVLTF- 1HSOA_Human THVLPFEKINEGFDLLhSGKSIRTILmF- 1HTBA_Human THVLPFEKINEGFDLLhSGKSIcTVLTF- Alligator_mississippiensis THtLPFDKINEGFELLRTGKSIRSVLTF- Apteryx_australis THtLPFiKINEGFDLLRkGKSIRSVLvF- Canis_lupus THVLPFEKINEGFDLLRSGKSIRTVLTF- Coturnix_coturnix THtLPFtKINEGFDLLRTGKSIRTVLvl- Gallus_gallus THtLPFtKINEGFDLLRTGKSIRSVLvl- Macaca_mulatta THVLPFEKINEGFDLLRSGKSIRTILTF- Mus_musculus THVLPFEKINEaFDLLRSGKSIRTVLTF- Oryctolagus_cuniculus TNVLPFEKINEGFDLLRSGKSIRTILTF- Pan_troglodytes THVLPFEKINEGFDLLhSGKSIRTVLTF- Papio_hamadryas THVLPFEKINEGFDLLRSGKSIRTVLTF- Pongo_pygmaeus THVLPFEKINDGFDLLhSGKSIRTILmF- Rattus_norvegicus THVLPFEKINEaFDLLRaGKSIRTVLTF- Struthio_camelus THtLPFhKINEGFDLLRTGKSIRSVLlF- ======================================================== Consensus THvLPFeKINEgFDLLRsGESIRTILtfx