Orotidine-5'-phosphate decarboxylase

10 20 30 40 50 60 70 ----:----|----:----|----:----|----:----|----:----|----:----|----:----|----: Consensus xxssktyxeraxxhxspvaxklxkimxxKqTnlcasLDvxSseExLklVExlgpyiclLKthVDIlndfsfextV ==================================================================================================== YEAST --SkaTYkERAatHpSPVAaKLfnIMheKQTNLCASLDVrTTKElLELVEaLGPkICLLKTHVDILtDFSmEgTV Candida_albicans tvNTKTYsERAetHaSPVAqRLfRLMesKKTNLCASIDVdTTKEfLELIDkLGPYVCLIKTHIDIINDFSYEsTI Candida_dubliniensis tvNTKTYsaRAetHaSPVAqRLfRLMesKKTNLCASIDVdTTKEfLELIDkLGPYVCLIKTHIDIINDFSYEsTI Candida_glabrata --SSaSYlQRAeaHpSPVAsKLlKLMheKKTNLCASLDVtTTsElLKLVDtLGPYICLLKTHVDILSDFSFEnTV Candida_tropicalis -vNTETYtERAskHpSkVAqRLfQLMesKKTNLCASIDVpTTKEfLsLIDkLGPFICLVKTHIDIISDFSYEgTI Debaryomyces_hansenii -vkTQTYtERAsaHpSPVAqRLfKLMdnKKTNLCASVDVkSTEEfLtLIEkLGPYICLVKTHIDIIDDFSYEgTV Eremothecium_gossypii --STKSYaERAkaHnSPVArKLlaLMheKKTNLCASLDVrTSrKlLELaDtLGPhICLLKTHVDILtDFdiEtTV Kluyveromyces_lactis --STKSYtsRAetHaSPVAsKLlRLMdeKKTNLCASLDVrSTDElLKLVEtLGPYICLLKTHVDILDDFSYEgTV Pichia_angusta ---yKSYgERAksHpSkVAsRLlnLMesKQTNLCASVDVtkTQElLELLDkLGPYICLVKTHIDIVeDFSYEhTI Zygosaccharomyces_bailii --STaTYhDRAakHaSPLAsKLlELMheKQTNLCASLDVdTTtElLRLVDiLGPYICLVKTHVDILSDFSmDgTV ==================================================================================================== BACILLUS_SUBTILIS ----------------------------KnnlpiiaLDfaSaEEtLafLapfqqeplfVKvgMELfyqegp-siV Bacillus_licheniformis ----------------------------nnTppiiaLDfaSaQEtyafLDrfqgeelfVKvgMELfyqegp-aiL ==================================================================================================== Consensus xxssktyxeraxxhxspvaxklxkimxxKqTnlcasLDvxSseExLklVExlgpyiclLKthVDIlndfsfextV 80 90 100 110 120 130 140 150 ----|----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus kpLkelxxkhnflLFeDrKfaDIgnTVklqysxgvyRIaexwaDItNaHgvtGxgIVeglkQgaEesTxxxqEpr ==================================================================================================== YEAST KPLKaLsaKyNFLLFEDRKFADIGNTVKLQYSaGVYRIAE-WADITNAHGVvGpGIVsGLKQaAEEvT---KEPR Candida_albicans EPLlELsrKHqFMIFEDRKFADIGNTVKkQYigGVYKIss-WADITNAHGVTGnGVVEGLKQGAKETTtn-QEPR Candida_dubliniensis EPLlELsrKHqFMIFEDRKFADIGNTVKkQYigGVYKIss-WADITNAHGVTGnGVVEGLKQGAKETTtd-QEPR Candida_glabrata KPLKEMaaKHNFLIFEDRKFADIGNTVKLQYTsGVYKIAE-WADITNAHGVTGqGIVtGLKQGAEETT---nEPR Candida_tropicalis lPLiELskKHNFMIFEDRKFADIGNTVKLQYTsGVYKIss-WsDITNAHGVTGkGgVEGLKKGADETT---nEPR Debaryomyces_hansenii vPLlaLakKHNFMIFEDRKFADIGNTVKsQYSgGVYKIAQ-WsDITNAHGITGsGIVKGLKEaAQESS---KEPR Eremothecium_gossypii KPLQQLaaKHNFMIFEDRKFADIGNTVKLQYSsGVYRIAE-WADITNAHGVTGpGVIaGLKEaAKlaS---QEPR Kluyveromyces_lactis vPLKaLaeKykFLIFEDRKFADIGNTVKLQYTsGVYRIAE-WsDITNAHGVTGaGIVaGLKQGAQEvT---KEPR Pichia_angusta lPLQgLakKHNFMIFEDRKFADIGNTVKLQYkgGIYRtsK-WADITNAHGVTGaGIVEGLKQaAEEST---dEPR Zygosaccharomyces_bailii KPLKELaaKHkFLIFEDRKFADIGNTVKLQYSsGVYQIsQ-WADITNAHGVTGpGIVQGLKQaAEETT---QEPR ==================================================================================================== BACILLUS_SUBTILIS KqLKEr----NceLFlDlKlhDIptTVnkamk----RLAslgvDLvNvHaagGkkMMQaalEGlEEgTpagKKrp Bacillus_licheniformis EnLQEr----gcrIFlDlKchDIptTVykamk----RLAgfgvsLvNvHaagGkqMMEsalEGlEagTpagQKrp ==================================================================================================== Consensus kpLkelxxkhnflLFeDrKfaDIgnTVklqysxgvyRIaexwaDItNaHgvtGxgIVeglkQgaEesTxxxqEpr 160 170 180 190 200 210 220 ----:----|----:----|----:----|----:----|----:----|----:----|----:----|----: Consensus gLLmLaELxSSkxxxxxxgsLaxxxxgEytkxtvEIAKsdkdfViGfIaqxxKdmggreegyxDWLiMTPGVgLd ==================================================================================================== YEAST GLLMLAEL-ScK------GSLst---GEYTKgTVDIAKSDKDFVIGFIAQ--RDMGGRDEGY-DWLIMTPGVGLD Candida_albicans GLLMLAEL-SSv------GSLAy---GEYSQkTVEIAKSDKEFVIGFIAQ--RDMGGQEEGF-DWLIMTPGVGLD Candida_dubliniensis GLLMLAEL-SSv------GSLAy---GEYSQkTVEIAKSDKEFVIGFIAQ--RDMGGQEEGF-DWIIMTPGVGLD Candida_glabrata GLLMLAEL-SSK------GSLAh---GEYTKgTVDIAKSDKDFVIGFIAQ--KDMGGRDEGF-DWLIMTPGVGLD Candida_tropicalis GLLMLAEL-SSK------GSLAy---GEYTnkTIEIAKSDKEFVIGFIAQ--RDMGGhDQGF-DWIIMTPGVGLD Debaryomyces_hansenii GLLMLAEL-SSK------GSLAy---GEYTEkTIEIAKSDKEFVIGFIAQ--RDMGGtDEGF-DWIVMTPGVGLD Eremothecium_gossypii GLLMLAEL-SSQ------GSLAr---GDYTagvVEMAKlDKDFVIGFIAQ--RDMGGRaDGF-DWLIMTPGVGLD Kluyveromyces_lactis GLLMLAEL-SSK------GSLAh---GEYTKgTVDIAKSDKDFVIGFIAQ--nDMGGREEGF-DWLIMTPGVGLD Pichia_angusta GLLMLAEL-SSK------GSLAt---GEYTQkTVEIAKSDKEFVIGFIAQ--RDMGGREEGF-DWLIMTPGVGLD Zygosaccharomyces_bailii GLLMLAEL-SSK------GSLAh---GEYTKgTVEIAKTDKDFVIGFIAQ--RDMGGRDEGY-DWLIMTPGVGLE ==================================================================================================== BACILLUS_SUBTILIS sLIaVtQLtSTseqimkdelLieksliDtvvhysKqAEe--sgLdGvVcsvhEakaiyQavspsFLtVTPGIrM- Bacillus_licheniformis sLIaVtQLtSTssemlqrelLietpllDtvvhysrLAEe--sgLdGvVcsvhEaehiyravsvDFLtVTPGIrM- ==================================================================================================== Consensus gLLmLaELxSSkxxxxxxgsLaxxxxgEytkxtvEIAKsdkdfViGfIaqxxKdmggreegyxDWLiMTPGVgLd 230 240 250 260 270 280 290 300 ----|----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus dEgdxlgxqQyrTvdevistGSdiIIVGRgLfxkgrDPevegeRyReagwdaylrrxgxxx ====================================================================================== YEAST DKGDaLG-QQYRTVDDVVSTGSDIIIVGRGLFaKGRDaKVEGERYRKAGWEAYLRRcGqqn Candida_albicans DKGDgLG-QQYRTVDEVVSTGTDIIIVGRGLFgKGRDPDIEGKRYRnAGWNAYLKKtGql- Candida_dubliniensis DKGDgLG-QQYRTVNEVVSTGTDIIIVGRGLFgKGRDPEVEGKRYRDAGWNAYLKKtGql- Candida_glabrata DKGDaLG-QQYRTVDEVfSTGTDIIIVGRGLFaKGRDPKtEGERYRKAGWDAYLKRiGn-- Candida_tropicalis DKGDaLG-QQYRTVDEVISTGTDVIIVGRGLFgKGRDPEVEGKRYREAGWNAYLKKnGqle Debaryomyces_hansenii DKGDgLG-QQYRTVDQVVTTGTDIIIVGRGLFgQGRDPtVEGKRYRDAGWNAYLKKtGsl- Eremothecium_gossypii DKGDgLG-QQYRTVDEVVSdGTDVIIVGRGLFdKGRDPnVEGaRYRKAGWEAYLRRiGets Kluyveromyces_lactis DKGDaLG-QQYRTVDEVVSgGSDIIIVGRGLFaKGRDPKVEGERYRnAGWEAYqKRisaph Pichia_angusta DKGDsLG-QQYRTVDEVMqTGTDVIIVGRGLFgKGRDPEVEGKRYRnAGWEAYkRRia--- Zygosaccharomyces_bailii DKsDaLG-QQYRTVEDVISTGSDIIIVGRGLFgKGRDPKIEGDRYRKAGWEAYLKRcnp-- ====================================================================================== BACILLUS_SUBTILIS sEdaandqvRvaTpaiarekGSsaIVVGRsItkae-DPvkayKavRlewegiks------- Bacillus_licheniformis aDdknndqvRvaTpgyarekGvsaIVVGRsItqae-DPvsayrRighewegtka------- ====================================================================================== Consensus dEgdxlgxqQyrTvdevistGSdiIIVGRgLfxkgrDPevegeRyReagwdaylrrxgxxx