500       510       520       530       540
                                  ----|----:----|----:----|----:----|----:----|
Consensus                         xxxmxqxlrxlxxlxeqxxixiIxsNqixxkvxxxxxxxxxxxxx
===============================================================================
PYROCOCCUS_FURIOSUS               -------------tlrvylrkgkg----------gkr--iarlid
Pyrococcus_abyssi                 -------------tlrvylrkgkg----------gkr--varlid
===============================================================================
METHANOCOCCUS_VOLTAE              ------------------tfrffvrkgkg----------dkr--v
Methanococcus_jannaschii          ------------------tfrIflrkakg----------dkr--v
===============================================================================
SULFOLOBUS_SOLFATARICUS           ----------------girIqLkkSrg----------nrr--iar
Aeropyrum_pernix                  ----------------gvrVyLkkSrg----------nkr--iar
Desulfurococcus_amylolyticus      ----------------gvrIqLrkSkg----------nkr--iar
Sulfolobus_tokodaii               ----------------girVqLkkSrg----------nkr--iar
===============================================================================
HUMAN                             --hLaRfLRmLlrLaDEfgVaVViTNQVvaQVd-g--a-a-----
YEAST                             --hLaKfMRaLqrLaDQfgVaVVvTNQVvaQVd-g--g-m-----
Apis_mellifera                    --hLgRfLRmLlrLaDEhgVaVViTNQVvaQVd-g--a-a-----
Aspergillus_fumigatus             --hLaKfMRtLqrLaDEfgIaVViTNQVvaQVd-ggps-a-----
Bombyx_mandarina                  --hLgRfMRmLlrLaDEfgVaVIiTNQVvaQVd-s--v-g-----
Bos_taurus                        --hLaRfLRmLlrLaDEfgVaVViTNQVvaQVd-g--a-a-----
Caenorhabditis_elegans            --kLsafLKcLakLaDEygVaVIiTNQVvaQVdgg--a-s-----
Candida_albicans                  --hVaKfMRtLqrLaDEfgIaVViTNQVvaQVd-g-ms-g-----
Candida_glabrata                  --hLaKfMRaLqrLaDQfgVaVVvTNQVvaQVd-g--g-m-----
Canis_lupus                       --hLaRfLRmLlrLaDEfgVaVViTNQVvaQVd-g--a-a-----
Coprinus_cinereus                 --hLgKfLRtLqrLaDEfgIaVVvTNQVmstpd-a--apg-----
Cricetulus_griseus                --hLaRfLRmLlrLaDEfgVaVViTNQVvaQVd-g--a-a-----
Cryptococcus_neoformans           --hLaKfLRtLmrLaDEfgVaVVvTNQVvaQVd-g--g-q-----
Danio_rerio                       --hLgRfLRmLlrLaDEfgVaVViTNQVvaQVd-g--a-a-----
Debaryomyces_hansenii             --hVaKyMRtLqrLaDEfgIaVViTNQVvaQVd-g--asa-----
Drosophila_melanogaster           --hLglfLRmLqrLaDEfgVaVViTNQVtasLd-g--a-p-----
Drosophila_pseudoobscura          --hLglcMRqLqrLaDEfgVaVViTNQVtaQLdgg--g-g-----
Emericella_nidulans               --hLaKfMRtLqrLaDEfgIaVViTNQVvaQVd-ggps-a-----
Encephalitozoon_cuniculi          --hLaKyLRsLvnLaEtfrIaVIiTNQVvsnVd-g--avg-----
Eremothecium_gossypii             --hLaKfMRaLqrLaDQfgVaVVvTNQVvaQVd-g--a-a-----
Gallus_gallus                     --hLaRfLRmLlrLaDEfgVaVViTNQVvaQVd-g--a-a-----
Gibberella_zeae                   --hLaKfMRtLqrLaDEfgIaVViTNQVvaQVd-ggps-a-----
Kluyveromyces_lactis              --hLaKfMRsLqrLaDQfgVaaVvTNQVvaQVd-g--g-m-----
Mus_musculus                      --hLaRfLRmLlrLaDEfgVaVViTNQVvaQVd-g--a-a-----
Neurospora_crassa                 --hLaKfMRtLqrLaDEfgIaVViTNQVvaQVd-ggps-a-----
Nosema_bombycis                   --sLaRyLRdLvnIaEtfhVaVIiTNQVvsnpd-g--ams-----
Oikopleura_dioica                 --hLgKfLRgLlkLaDtfgVaIViTNQVtanVd-g----------
Oryctolagus_cuniculus             --hLaRfLRmLlrLaDEfgVtVViTNQVvaQVd-g--a-a-----
Pichia_angusta                    --hVaKfMRtLqrLaDEfgIaVViTNQVvaQVd-g--g-a-----
Pleurotus_ostreatus               --hLgKfLRtLqrLaDEfgIaVViTNQVmsnpd-a--a-a-----
Rattus_norvegicus                 --hLaRfLRmLlrLaDEfgVaVViTNQVvaQVd-g--a-a-----
Schizosaccharomyces_pombe         --hLaRfMRtLqrLaDEfgIaVViTNQVvaQVd-g--i-s-----
Strongylocentrotus_purpuratus     --hLgRfLRtLlrLaDEygVaVViTNQVvaQVd-g--a-a-----
Tetraodon_nigroviridis            gggtgRrgRhVfrrsQEthwrqhsgSRfyhpVs-g--v-f-----
Ustilago_maydis                   --hLaKfLRgLmrLaDEfgVaVViTNQVvaQVd-g--a-t-----
Xenopus_laevis                    --hLaRfLRmLlrLaDEfgVaVViTNQVvaQVd-g--a-a-----
Xenopus_tropicalis                --hLaRfLRmLlrLaDEfgVaVViTNQVvaQVd-g--a-a-----
Yarrowia_lipolytica               --hVaKfMRtLqrLaDEfgIaVViTNQVvaQVd-g--a-v-----
Cryptosporidium_spp               --hLgQfLRaLqkIaDtfgVaVViTNQVmsKVd-a--m-a-----
Dictyostelium_discoideum          --hLaRfLRtLqrLaDEfgVaVViTNQVvasVd-g--agg-----
Entamoeba_histolytica             --hLvKfLRaLqrIaDEfsVaVVlTNQVvaQVd-g-qa-s-----
Leishmania_donovani               --hLgKfLRsLhnLaEEygVaVVvTNQVvanVd-g--saq-----
Leishmania_tropica                --hLgKfLRsLhnLaEEygVaVVvTNQVvanVd-g--s-a-----
Plasmodium_berghei                --hLcRfLRgLqrIaDiygVaVIiTNQVvaKVd-a--m-s-----
Plasmodium_falciparum             --hLcRfLRgLqrIaDiygVaVIiTNQVvaKVd-a--m-s-----
Plasmodium_yoelii                 --hLcRfLRgLqrIaDiygVaVIiTNQVvaKVd-a--m-s-----
Tetrahymena_thermophila           --hLgKfLRnLqrLaDEfgIaVViTNQVmsQVd-g--a-a-----
Theileria_annulata                --hLcKfLRaLqrIaDtfgVaVViTNQVvaRVd-a--m-stffgi
Theileria_parva                   --hLcKfLRaLqrIaDtfgVaVViTNQVvaKVd-a--m-s-----
Trypanosoma_brucei                --hLgKfLRsLrnLanEynVaVVvTNQVvanVd-g--a-ap----
Trypanosoma_cruzi                 --hLgKfLRsLhnLaEEygVaVVvTNQVvanVd-g--s-a-----
Arabidopsis_thaliana              --hLaKfLRsLqkLaDEfgVaVViTNQVvaQVd-g--s-a-----
Oryza_sativa                      --hMaKfLRsLqkLaDEfgVaVViTNQVvaQVd-g--s-a-----
Zea_mays                          --hLaKfLRsLqkLaDEfgVaVViTNQVvaQVd-g--a-a-----
===============================================================================
ECOLI                             --mMsQaMRkLagnlKQsntlLIfiNQIrmKIgvmfg--npettt
MYCOBACTERIUM_SMEGMATIS           --lMsQaLRkMtgalnnsgttaIfiNQLreKIgvmfg--spettt
MYCOBACTERIUM_TUBERCULOSIS        --lMsQaLRkMtgalnnsgttaIfiNQLreKIgvmfg--spettt
Acetobacter_polyoxogenes          --lMsQaLRkLtgsvsRsntmLIflNQIrlKIgvmfg--spestt
Acinetobacter_calcoaceticus       --lMsQaLRkItgnaKRsncmVIfiNQIrmKIgvmfg--spettt
Actinobacillus_pleuropneumoniae   --lMsQaLRkLtaniKatnclVVfiNQIrmKIgvmfg--npettt
Actinobacillus_succinogenes       --lMsQaLRkLtaqiKssnclVVfiNQIrmKIgvmfg--npettt
Bacillus_licheniformis            --lMsQaLRkLsgainKsktiaIfiNQIreKVgvmfg--npettp
Bacillus_subtilis                 --lMsQaLRkLsgainKsktiaIfiNQIreKVgvmfg--npettp
Burkholderia_fungorum             --lMsQaLRkLtgtiKRtnclVIfiNQIrmKIgvmfg--npettt
Carboxydothermus_hydrogenoformans --lMsQaLRkLtgaisKsktvaIfiNQMreKVgvmfg--npettp
Chromobacterium_violaceum         --lMsQaLRkLtgniKRtntlVIfiNQIrmKIgvmfg--npettt
Clostridium_thermocellum          --lMsQaLRkLagVinKsrttaIfiNQLreKVgvmfg--npettp
Colwellia_psychrerythraea         --mLsQaMRkLtgnlKKsntmLIfiNQIrmKIgvmfg--spettt
Desulfotalea_psychrophila         --lMsQaMRkfagVlnRsntvLIfiNQIrmKIgvmfg--spettt
Enterococcus_faecalis             --lMsQaLRkLsgsinKtktiaIfiNQIreKVgvmfg--npettp
Erwinia_carotovora                --mMsQaMRkLagnlKQantlLIfiNQIrmKIgvmfg--npettt
Haemophilus_ducreyi               --lMsQaLRkLtaniKatnclVVfiNQIrmKIgvmfg--npettt
Haemophilus_influenzae            --lMsQaLRkLtgqiKnanclVVfiNQIrmKIgvmfg--npettt
Histophilus_somni                 --lMsQaLRkLtgqiKnsnclVVfiNQIrmKIgvifg--npettt
Kineococcus_radiotolerans         --lMsQaLRkItgalnhsgttaIfiNQLreKIgvmfg--spettt
Leifsonia_xyli                    --lMsQaLRkLtgalsQtnttMIfiNQLreKVgvffg--spetta
Listeria_monocytogenes            --lMsQaLRkLsgVinKsktiaIfiNQIreKVgvmfg--npeitp
Mannheimia_succiniciproducens     --lMsQaLRkLtgqiKnanclVVfiNQIrmKIgvmfg--npettt
Neisseria_gonorrhoeae             --lMsQaLRkLtghiKKtntlVVfiNQIrmKIgvmfg--spettt
Nitrosomonas_europaea             --lMsQaLRkLtaniKRtntmVIfiNQIrmKIgvifg--npettt
Nitrosomonas_eutropha             --lMsQaLRkLtaniKRtnttVIfiNQIrmKIgvmfg--npettt
Oceanobacillus_iheyensis          --lMsQaLRkLsgainKskttaIfiNQIreKVgvmfg--npettp
Pasteurella_multocida             --mLsQaMRkLtgnlKQsncmcIfiNQIrmKIgvmfg--npettt
Photobacterium_profundum          --mLsQaMRkLtgnlKnancmcIfiNQIrmKIgvmfg--npettt
Photorhabdus_luminescens          --mMsQaMRkLagnlKssntlLIfiNQIrmKIgvmfg--npettt
Proteus_mirabilis                 --mMsQaMRkLagnlKnsntlLIfiNQIrmKIgvmfg--npettt
Pseudomonas_aeruginosa            --mMsQaMRkItgnlKnsntmcIfiNQIrmKIgvmfg--npettt
Pseudomonas_cepacia               --lMsQaLRkLtgtiKRtnclVIfiNQIrmKIgvmfg--npettt
Salmonella_typhi                  --mMsQaMRkLagnlKQsntlLIfiNQIrmKIgvmfg--npettt
Shewanella_putrefaciens           --mMsQaMRkLagnlKQsntlLIfiNQIrmKIgvmfg--npettt
Streptomyces_avermitilis          --lMsQaLRkItsalnQskttaIfiNQLreKIgvmfg--spettt
Streptomyces_coelicolor           --lMsQaLRkItsalnQskttaIfiNQLreKIgvmfg--spettt
Streptomyces_lividans             --lMsQaLRkItsalnQskttaIfiNQLreKIgvmfg--spettt
Vibrio_cholerae                   --mLsQaMRkLtgnlKQsncmcIfiNQIrmKIgvmfg--npettt
Vibrio_splendidus                 --mLsQaMRkLtgnlKQsncmaIfiNQIrmKIgvmfg--npettt
Vibrio_vulnificus                 --mLsQaMRkLtgnlKQsncmcIfiNQIrmKIgvmfg--npettt
Xanthomonas_vasicola              --lMsQaLRkLtgniKRsntlVVfiNQLrmKIgvmmpgqspevtt
Xylella_fastidiosa                --lMsQaLRkLtgniKRsntlVIfiNQLrmKIgimmpgqspettt
Yersinia_pestis                   --mMsQaMRkLagnlKnantlLIfiNQIrmKIgvmfg--npettt
===============================================================================
DEINOCOCCUS_RADIODURANS           ---------------------sVrlDvrkigqptkvgndavantv
Deinococcus_geothermalis          ---------------------sVrlDvrkigqpvklgndavgntv
Thermus_aquaticus                 ---------------------sVrlDvrksgqpikvgneavgikv
===============================================================================
Consensus                         xxxmxqxlrxlxxlxeqxxixiIxsNqixxkvxxxxxxxxxxxxx