10        20        30        40        50        60        70
                              ----:----|----:----|----:----|----:----|----:----|----:----|----:----|
Consensus                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
====================================================================================================
PYRFU                         ----------------------------------------------------------------------
Pyrococcus_abyssi             ----------------------------------------------------------------------
====================================================================================================
HUMAN                         -----------------------------------------------------------qqqqq----qq
YEAST                         ----------------------------------------------------------------------
ARABIDOPSIS_THALIANA          ----------------------------------------------------------------------
1JFIC_Human                   ----------------------------------------------------------------------
1TBPA_Yeast                   ----------------------------------------------------------------------
Anopheles_gambiae             -------------------------dqmlpspgfs-----------ipsigt-------plhqp----ee
Apis_mellifera                ---dqmlp-----spgfsipsigtp--lhqpeedqqil----pnal-------------qqqqq----qq
Aspergillus_fumigatus         -esltth--------pstaqqaraftspasl-sfpg-gagdltppssekegnitigaqgangtvnghqqg
Bombyx_mandarina              dhmlpspy-----nipgigtplhqpeedqqilpnam-------qqqqlqq-------qqsqaqpslaalg
Bos_taurus                    --------------------------drndslspfdqylaspqgamspgipvfspvmhygtglt----pq
Caenorhabditis_briggsae       nmnspasrsmmggetpahggpssvlggpssiltg--hgpnsvmgpnsilg-pgs--mvnpqsiqpmqsh-
Caenorhabditis_elegans        nlnspavs-----mlggdtpahggpnsvlggqgpssiltghgpnsvmgpnsilgpgsvlnpqsi----qp
Candida_albicans              ----------------------------------------------------------------------
Candida_glabrata              ----------------------------------------------------------------------
Canis_lupus                   ----------------------------------------------------------------------
Cryptococcus_neoformans       ----------------------------------------------------------------------
Danio_rerio                   ----eqnn-----slppfaqglaspqgamt-pglpif-spmmpygtgltpqp----vqnsn---------
Debaryomyces_hansenii         ----------------------------------------------------------------------
Drosophila_melanogaster       dqmlspnf-----sipsigtplhqmeadqqivanpvyhppavsqpdslmpapgsssvqhqqqqqqsdasg
Drosophila_pseudoobscura      dqmlspnf-----sipsigtpmhqmeadqqiianpvyhppaipqpepaisapvpvagqqqqpdasnattg
Emericella_nidulans           ------------------------------------------------------------dslt----th
Encephalitozoon_cuniculi      ----------------------------------------------------------------------
Eremothecium_gossypii         ----------------------------------------------------------------------
Gallus_gallus                 ------------------dqnnslppyaqglaspqgamtpgip--ifsp--mm-p----ygtgl----tp
Gibberella_zeae               ----egiq-----thpsnaaqakaftapgslsfpgatneltpp--pvgngda-tqqpphngqqaa-----
Kluyveromyces_lactis          ----------------------------------------------------------------------
Magnaporthe_grisea            ----------------------------------------------------------------------
Mesocricetus_auratus          ----dqnn-----slppyaqglaspqgam-tpgipif-spmmpygtgltpqpiqntnslsilee----qq
Mus_musculus                  ---dqnns-------l--ppyaqglaspqgamtpg--ipifspmmpygtg--ltpqpi-qntnslsilee
Neurospora_crassa             ----------------------------------------------------------------------
Petromyzon_marinus            ----dssg-----smpgfspnlgsqqgg--mtpgm-----------plf----------spmmpygtglt
Pneumocystis_carinii          ----------------------------------------------------------------------
Rattus_norvegicus             ----dqnn-----slppyaqglaspqgam-tpgipif-spmmpygtgltpqpvqntnslsilee----qq
Schizosaccharomyces_pombe     ----------------------------------------------------------------------
Strongylocentrotus_purpuratus -----------------------------------------------------------ynpsq----av
Tetraodon_nigroviridis        -----------------------desaleryfedsiandsgf-lleeelsigsptlsstylpgkaglsrg
Ustilago_maydis               ----------------------------------------------------------------------
Xenopus_laevis                ----------------------dqnnsippfqglas-----pqgsltpginifsp----lityg----tg
Xenopus_tropicalis            ----------------------dqnnsippfqglas-----pqgsltpginifsp----lmpyg----tg
Yarrowia_lipolytica           ----------------------------------------------------------------------
Dictyostelium_discoideum      -----------------------------------------------------------st---------
Tetrahymena_thermophila       ---------------------ssdktsqqtfk-la-----------------------------------
Glycine_max                   ----------------------------------------------------------------------
Oryza_sativa                  ----------------------------------------------------------------------
Zea_mays                      ----------------------------------------------------------------------
====================================================================================================
Consensus                     xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx