TBP (TATA-binding protein, TF2D)

500 510 520 530 540 550 560 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus EgLxxshxxfssYEPElFPGLIYRMiqPRiVLLIFvSGKVVlTGAKvKeDiyeAfdxIfpiLexxxxxfr ==================================================================================================== PYRFU DvValTlp-nceYEPEqFPGVIYRVkEPKsVILLFsSGKIVcSGAKsEaDaWEAvrkLlreLDk------ Pyrococcus_abyssi DnValTlp-nceYEPEqFPGVIYRVkdPRaVILLFsSGKIVcSGAKsEaDaWEAvrkLlreLEk------ ==================================================================================================== HUMAN EGLvlTHqqFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRaEIYEAFEnIYPILKg----FR YEAST EGLafSHgtFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKqREEIYQAFEaIYPVLse----FR ARABIDOPSIS_THALIANA EGLaySHaaFSSYEPELFPGLIYRMkvPKIVLLIFVSGKIVITGAKMRDEtYKAFEnIYPVLse----FR 1JFIC_Human EGLvlTHqqFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRaEIYEAFEnIYPILKg----FR 1TBPA_Yeast EGLafSHgtFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKqREEIYQAFEaIYPVLse----FR Anopheles_gambiae EGLvlTHgrFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRQEIYDAFEnIYPILKs----FK Apis_mellifera EGLvlTHgqFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRQEIYEAFDnIYPILKs----FK Aspergillus_fumigatus EGLasrHhnFSSYEPELFPGLIYRMMKPKIVLLIFVSGKIVLTGAKVREEIYQAFElIYPVLsgtvilFf Bombyx_mandarina EGLvlTHgqFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVREEIYEAFDnIYPILKs----FK Bos_taurus EpLvlSHqqFaSYEPELFPGLVYRMIKPRIVLLIFVSGKVVLTGAKVRsEIYEAFNnIYsILKg----FR Caenorhabditis_briggsae EGLciTHaqFSTYEPELFPGLIYRMVKPRVVLLIFVSGKVVITGAKtKKDIdDAFgqIYPILKg----FK Caenorhabditis_elegans EGLciTHsqFSTYEPELFPGLIYRMVKPRVVLLIFVSGKVVITGAKtKrDIdEAFgqIYPILKg----FK Candida_albicans EGLafaHgtFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKkREEIYDAFEsIYPVLne----FR Candida_glabrata EGLafSHgtFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKqREEIYQAFEaIYPVLse----FR Canis_lupus EGLvlTHqqFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRaEIYEAFEnIYPILKg----FR Cryptococcus_neoformans EGLafSHgaFSSYEPELFPGLIYRMLKPKVVILIFVSGKIVLTGAKVREEIYmAFNqIYsVLle----FR Danio_rerio EGLvlTHqqFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRgEIYEAFEnIYPILKg----FR Debaryomyces_hansenii EGLafSHgtFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKqREEIYaAFEaIYPVLse----FR Drosophila_melanogaster EGLvlTHcnFSSYEPELFPGLIYRMVRPRIVLLIFVSGKVVLTGAKVRQEIYDAFDkIFPILKk----FK Drosophila_pseudoobscura EGLvlTHcnFSSYEPELFPGLIYRMVRPRIVLLIFVSGKVVLTGAKVRQEIYDAFDkIFPILKk----FK Emericella_nidulans EGLasrHhnFSSYEPELFPGLIYRMMKPKIVLLIFVSGKIVLTGAKVREEIYQAFElIYPVLsd----FR Encephalitozoon_cuniculi EGLayaHsnYcSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKVRDDIYQAFNnIYPVLiq----hR Eremothecium_gossypii EGLafSHgtFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKqREEIYQAFEaIYPVLse----FR Gallus_gallus EGLvlTHqqFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRaEIYEAFEnIYPILKg----FR Gibberella_zeae EGLasrHhnFSSYEPELFPGLIYRMIKPKIVLLIFVSGKIVLTGAKVREEIYQAFEmIYPVLQg----lR Kluyveromyces_lactis EGLafSHgtFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKqREEIYQAFEaIYPVLse----FR Magnaporthe_grisea EGLasrHhnFSSYEPELFPGLIYRMIKPKIVLLIFVSGKIVLTGAKVREEIYQAFEmIYPVLQd----FR Mesocricetus_auratus EGLvlTHqqFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRaEIYEAFEnIYPILKg----FR Mus_musculus EGLvlTHqqFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRaEIYEAFEnIYPILKg----FR Neurospora_crassa EGLaskHhnFSSYEPELFPGLIYRMIKPKIVLLIFVSGKIVLTGAKVREEIYQAFEmIYPVLQd----FR Petromyzon_marinus EGLvlTHqqFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRgEIYEAFEnIYPILKg----FR Pneumocystis_carinii EGLaySHgtFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKVREEIYQAFEaIYPVLse----FR Rattus_norvegicus EGLvlTHqqFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRaEIYEAFEnIYPILKg----FR Schizosaccharomyces_pombe EGLaySHgtFSSYEPELFPGLIYRMVKPKVVLLIFVSGKIVLTGAKVREEIYQAFEaIYPVLse----FR Strongylocentrotus_purpuratus EGLvlTHgqFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKVRQEIYDAFNnIYPILKs----FK Tetraodon_nigroviridis EGLvlTHqqFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKeRaEIYEAFEnIYPILrg----FR Ustilago_maydis EGLaySHgvYSSYEPELFPGLIYRMVKPKVVLLIFVSGKIVLTGAKVREEIYQAFNlIlPVLae----FR Xenopus_laevis EGLvlTHqqFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRaEIYEAFEnIYPILKg----FR Xenopus_tropicalis EGLvlTHqqFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRaEIYEAFEnIYPILKg----FR Yarrowia_lipolytica EGLafSHgtFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKqREEIYaAFEaIYPVLne----FR Dictyostelium_discoideum ElLhnaHtsFTNYEPEIFPGLIYKMIQPKVLLLIFVSGKIVLTGAKVREyIYEAFEnIYPVLsa----FK Tetrahymena_thermophila DhLeqdHkkFvqYEPEIFPGkIYRefntKIVLLIFVSGKIVLTGAKtRENInKAFqkIYwVLyn----YQ Glycine_max EGLaySHgaFSSYEPELFPGLIYRMkQPKIVLLIFVSGKIVLTGAKVRDEtYtAFEnIYPVLte----FR Oryza_sativa EGLaySHgaFSSYEPELFPGLIYRMkQPKIVLLIFVSGKIVLTGAKVRDEtYtAFEnIYPVLte----FR Zea_mays EGLaySHgaFSSYEPELFPGLIYRMkQPKIVLLIFVSGKIVLTGAKVREEtYtAFEnIYPVLse----FR ==================================================================================================== Consensus EgLxxshxxfssYEPElFPGLIYRMiqPRiVLLIFvSGKVVlTGAKvKeDiyeAfdxIfpiLexxxxxfr

TBP (TATA-binding protein, TF2D)

Page 8 of 9